지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Although biologics are highly effective in psoriasis, they have significant effects on innate and adaptive immune systems that may negatively impact on mechanisms of cancer immunosurveillance. However, there are limited data on the risk of cancer in psoriasis patients treated with biologics. A 70 years-old male patient presented with plaque psoriasis for four years’ duration. After receiving methotrexate for nine months, guselkumab was started due to inefficacy. After two years of guselkumab therapy, he visited the otolaryngologist with the voice change and pain around the left jaw for one year. The result of laryngoscopic biopsy showed a left supraglottic squamous cell carcinoma, and there was no metastasis on additional imaging studies. He was transferred to another hospital for surgery and concurrent chemoradiation therapy, and continues guselkumab treatment. Herein, we report on a case of laryngeal cancer during guselkumab treatment in a patient with psoriasis with the review of literatures.
목차
등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
Lee JH / 2019 / Cancer risk in 892 089 patients with psoriasis in Korea : A nationwide population-based cohort study / Journal of Dermatology 46:95~102
Gelfand JM / 2003 / Lymphoma rates are low but increased in patients with psoriasis : results from a population-based cohort study in the United Kingdom / Arch Dermatol 139:1425~1429
Boffetta P / 2001 / Cancer risk in a population-based cohort of patients hospitalized for psoriasis in Sweden / J Invest Dermatol 117:1531~1537
Chiesa Fuxench ZC / 2016 / The risk of cancer in patients with psoriasis : a population-based cohort study in the health improvement network / JAMA Dermatol 152:282~290
Lee JW / 2019 / Risk of malignancy in patients with psoriasis : a 15-year nationwide populationbased prospective cohort study in Korea / J Eur Acad Dermatol Venereol 33:2296~2304
Gelfand JM / 2003 / Lymphoma rates are low but increased in patients with psoriasis : results from a population-based cohort study in the United Kingdom / Arch Dermatol 139:1425~1429
Boffetta P / 2001 / Cancer risk in a population-based cohort of patients hospitalized for psoriasis in Sweden / J Invest Dermatol 117:1531~1537
Chiesa Fuxench ZC / 2016 / The risk of cancer in patients with psoriasis : a population-based cohort study in the health improvement network / JAMA Dermatol 152:282~290
Lee JW / 2019 / Risk of malignancy in patients with psoriasis : a 15-year nationwide populationbased prospective cohort study in Korea / J Eur Acad Dermatol Venereol 33:2296~2304
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