지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 충북대학교 동물의학연구소 Journal of Biomedical and Translational Research Journal of Biomedical and Translational Research 제22권 제4호
- 발행연도
- 2021.12
- 수록면
- 205 - 209 (5page)
이용수
초록· 키워드
오류제보하기
Testicular germ cell tumors (GCT) arise from embryonic or extraembryonic differentiated totipotential germ cells. The tumor cells can differentiate into germ cells as well as, other lin-eages including yolk sac tumors, choriocarcinomas, and teratomas. Mixed GCT is composed of more than one GCT component including one or more nonseminomatous elements in a tumor, accounting for one-third of GCT. Herein we report the case of a collision tumor with two distinct and separated GCTs in the testis, adjacent to each other. A 48-year-old, pre-viously healthy man showed the hard swelling and heterogeneous enhancing mass in the right scrotum, and right orchiectomy was performed. Grossly, the lesion was two distinct and well-circumscribed masses in the testis. Microscopically, a larger tumor was immature terato-ma (prepubertal type) and another smaller tumor was seminoma. These two tumors can be from a common precursor, germ cell neoplasia in situ (GCNIS); however, they are two distinct pathological entities. Given that teratomas can evolve from seminomas by additional genetic alterations, seminomas are also a precursor for postpubertal-type teratomas. Two distinct GCNISs may occur at different times. Because GCNIS is patchy distributed, a close gross examination must be performed in GCNIS or GCT to miss other GCTs with poor prognosis and to prevent under-treatment
목차
등록된 정보가 없습니다.
참고문헌 (8)
참고문헌 신청
Krag Jacobsen G / 1984 / Testicular germ cell tumours in Denmark 1976–1980 pathology of 1058 consecutive cases / Acta Radiol Oncol 23:239~247
Murthaiah P / 2009 / Collision tumor versus multiphenotypic differentiation : a case of carcinoma with features of colonic and lung primary tumors / Anticancer Res 29:1495~1497
Woo CG / 2019 / Collision tumor comprising metastatic cholangiocarcinoma and seminoma in an undescended testis : a case report / J Int Med Res 47:5809~5816
Stoop H / 2008 / Stem cell factor as a novel diagnostic marker for early malignant germ cells / J Pathol 216:43~54
Srigley JR / 1988 / The ultrastructure and histogenesis of male germ neoplasia with emphasis on seminoma with early carcinomatous features / Ultrastruct Pathol 12:67~86
Murthaiah P / 2009 / Collision tumor versus multiphenotypic differentiation : a case of carcinoma with features of colonic and lung primary tumors / Anticancer Res 29:1495~1497
Woo CG / 2019 / Collision tumor comprising metastatic cholangiocarcinoma and seminoma in an undescended testis : a case report / J Int Med Res 47:5809~5816
Stoop H / 2008 / Stem cell factor as a novel diagnostic marker for early malignant germ cells / J Pathol 216:43~54
Srigley JR / 1988 / The ultrastructure and histogenesis of male germ neoplasia with emphasis on seminoma with early carcinomatous features / Ultrastruct Pathol 12:67~86
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