지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 충북대학교 동물의학연구소 Journal of Biomedical and Translational Research Journal of Biomedical and Translational Research 제22권 제4호
- 발행연도
- 2021.12
- 수록면
- 179 - 188 (10page)
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초록· 키워드
오류제보하기
We conducted diagnostic investigations to analyze the causes of abortions (46 cases, 65.7%), deaths (22 cases, 31.4%) and muscular lesions (2 cases, 2.9%) occurred after foot and mouth disease (FMD) vaccination in livestock farms in Korea. Bacterial culture, enzyme-linked immunosorbent assay (ELISA) and polymerase chain reaction (PCR) were performed to detect the causative agents of abortion in bovine and caprine. The diagnostic results showed that 36 (51.4%) cases, referring as “Identified”, were occurred by influence of underlying disease including bovine viral diarrhea (12 cases, 17.1%), neosporosis (7 cases, 10.0%), septicemic colibacillosis (5 cases, 7.1%), Q fever (4 cases, 5.7%) and other abnor-mal conditions (8 cases, 11.4%) not by vaccination. Other 2 (3.0%) cases were suspected to be vaccine-associated adverse reaction on the basis of pathological findings (shock lung, oil-component-induced granuloma) and clinical symptoms (dyspnea with pulmonary ede-ma). The other 32 (45.7%) cases were determined “Unknown” because any pathogens and pathological changes were not identified. However, many of the “Unknown” cases were pre-sumptive to be the vaccine-related adverse reaction based on epidemiological investigation, especially, the cases which showed the clinical signs within 2 days after the vaccination. It is important to conduct pathological, microbilogical and epidemiological investigation to diag nose whether the cases are from vaccine-associated adverse reaction or not.
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Park JH / 2013 / Requirements for improved vaccines against foot-and-mouth disease epidemics / Clin Exp Vaccine Res 2:8~18
Animal and Plant Quarantine Agency [APQA] / 2015 / Standard guidelines for animal diagnosis, APQA Article 14
Romero C / 1995 / Specific detection of Brucella DNA by PCR / J Clin Microbiol 33:615~617
Vaidya VM / 2008 / Comparison of PCR, immunofluorescence assay, and pathogen isolation for diagnosis of Q-fever in humans with spontaneous abortions / J Clin Microbiol 46:2038~2044
Aznar R / 2003 / PCR detection of Listeria monocytogenes : a study of multiple factors affecting sensitivity / J Appl Microbiol 95:958~966
Animal and Plant Quarantine Agency [APQA] / 2015 / Standard guidelines for animal diagnosis, APQA Article 14
Romero C / 1995 / Specific detection of Brucella DNA by PCR / J Clin Microbiol 33:615~617
Vaidya VM / 2008 / Comparison of PCR, immunofluorescence assay, and pathogen isolation for diagnosis of Q-fever in humans with spontaneous abortions / J Clin Microbiol 46:2038~2044
Aznar R / 2003 / PCR detection of Listeria monocytogenes : a study of multiple factors affecting sensitivity / J Appl Microbiol 95:958~966
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