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논문 기본 정보

자료유형
학술저널
저자정보
Denise Zdzieblik (CRI Collagen Research Institute Kiel Germany) Steffen Oesser (Collagen Research Institute) Daniel König (University of Vienna)
저널정보
대한골대사학회 대한골대사학회지 대한골대사학회지 제28권 제3호
발행연도
2021.8
수록면
207 - 213 (7page)

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초록· 키워드

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Background: The effects of specific collagen peptides on bone mineral density (BMD) in subjects with osteoporosis or osteopenia have already been investigated in 131 postmenopausal women in a randomized controlled trial. The purpose of this follow-up observation was to determine the longer-term effects of the same specific bioactive collagen peptides after a total intervention time of 4 years. Methods: In this open-label follow-up observation, 31 postmenopausal women with reduced BMD (initial T-score lower than?1 of either the femoral neck or the lumbar spine) completed the follow-up. BMD was measured via dual energy X-ray absorptiometry. Absolute changes in BMD and T-scores in the spine and femoral neck were assessed. The number of fractures was also recorded. All participants received specific bioactive collagen peptides. Results: Supplementation with bioactive collagen peptides during follow-up led to a clinically relevant increase in BMD in the spine. These findings were consistent with the results for the femoral neck. Conclusions: Long-term supplementation with specific bioactive collagen peptides appears to be effective in counteracting losses in BMD. Moreover, significant increases in BMD could contribute to improved bone stability.

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