Evaluation of the Macular and Choroidal Perfusion in Healthy Turkish Population Using Optical Coherence Tomography Angiography

Mahmut Kaya; Ziya Ayhan; Arif Taylan Ozturk; Nilufer Kocak; Gul Arikan; Suleyman Kaynak

doi:10.3341/kjo.2020.0122

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저자정보: Mahmut Kaya (Dokuz Eylul University School of Medicine) Ziya Ayhan (Dokuz Eylul University School of Medicine) Arif Taylan Ozturk (Dokuz Eylul University School of Medicine) Nilufer Kocak (Dokuz Eylul University School of Medicine) Gul Arikan (Dokuz Eylul University School of Medicine) Suleyman Kaynak (Dokuz Eylul University School of Medicine)

저널정보: 대한안과학회 Korean Journal of Ophthalmology Korean Journal of Ophthalmology 제35권 제5호

발행연도: 2021.10

수록면: 360 - 367 (8page)

DOI: 10.3341/kjo.2020.0122

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Purpose: To investigate the effect of age- and sex-related differences on macular and choroidal perfusion in healthy Turkishindividuals by optical coherence tomography angiography (OCTA). Methods: Two hundred-eight eyes of 116 healthy Turkish individuals (60 females and 56 males, mean age 40.35 ± 12.64years) were included in this study. OCTA was performed on a 3 × 3-mm region on the macula. The superficial macula wholeimagevessel density (wiVD), foveal VD and parafoveal VD vessel density, foveal avascular zone (FAZ) as well as choriocapillarisflow index (CFI) were quantified. Results: The mean vessel density was 53.1% ± 2.8% in superficial macula wiVD, 31.7% ± 6.9% in superficial foveal VD and55.2% ± 3.4% in superficial parafoveal VD for 3 × 3-mm OCTA images. Analysis of 3 × 3-mm scan has revealed a mean valueof FAZ area was 0.313 ± 0.112 mm2. The mean CFI for 3 × 3-mm scan was 1.937 ± 0.059. A significant decrease was observedin the mean values of wiVD, parafoveal VD and CFI with age (p < 0.001, p = 0.001, and p < 0.001, respectively), with averageyearly reductions of 0.3%, 0.4% and 0.4%, respectively. However, there was no correlation between age and foveal VD (p >0.05). The FAZ area has shown an age-dependent annual increment, showing an average of 1.26%. The parafoveal VD and FAZarea were significantly higher in females than males (p = 0.027 and p = 0.015, respectively) while other parameters seemedsimilar (p > 0.05 for all). Conclusions: Our results suggest that age- and sex-related variations were effective on macular and choroidal perfusion. These normative values obtained using OCTA may be clinically useful to the evaluation of retinal and choroidal disorders.

#Age #Choroidal perfusion #Macular perfusion #Optical coherence tomography angiography #Sex

참고문헌 (32)

참고문헌 신청

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