지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.11
- 수록면
- 857 - 863 (7page)
- DOI
- 10.5946/ce.2021.028
이용수
초록· 키워드
오류제보하기
Background/Aims: Esophageal variceal bleeding (EVB) is an important cause of mortality and morbidity in liver cirrhosis. In thisstudy, we aimed to predict the possibility of EVB in patients with cirrhosis using a non-invasive score.
Methods: A total of 359 patients with cirrhosis were divided into two groups based on the presence or absence of EVB. Child-Turcotte-Pugh (CTP) score, a model for end-stage liver disease, aspartate aminotransferase to alanine aminotransferase ratio,aspartate aminotransferase to platelet ratio index (APRI), fibrosis-4-index (FIB-4), aspartate aminotransferase to alanineaminotransferase ratio/platelet ratio index (AARPRI), and S-index were measured for all participants. Receiver operatingcharacteristic curves were obtained for all parameters, and the optimal cut-off value was determined in predicting EVB.
Results: In patients with EVB, the number of platelets (PLT) were low (p<0.001) and APRI, AARPRI, FIB-4, and S-index weresignificantly higher than those in patients without EBV. APRI, AARPRI, FIB-4, PLT, and S-index were statistically significantpredictors of EVB (p<0.05).
Conclusions: FIB-4 and AARPRI, which are non-invasive markers of fibrosis, can be used to predict EVB. In addition, the 66.5 109/Lcut-off value for PLT is important for EVB.
목차
등록된 정보가 없습니다.
참고문헌 (34)
참고문헌 신청
Rahimi RS / 2011 / Complications and outcomes in chronic liver disease / Curr Opin Gastroenterol 27:204~209
Ripoll C / 2007 / Hepatic venous pressure gradient predicts clinical decompensation in patients with compensated cirrhosis / Gastroenterology 133:481~488
de Franchis R / 2015 / Expanding consensus in portal hypertension:report of the Baveno VI Consensus Workshop: stratifying risk and individualizing care for portal hypertension / J Hepatol 63:743~752
Garcia-Tsao G / 2007 / Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis / Hepatology 46:922~938
Garcia-Tsao G / 2017 / Portal hypertensive bleeding in cirrhosis : risk stratification, diagnosis, and management : 2016 practice guidance by the American Association for the study of liver diseases / Hepatology 65:310~335
Ripoll C / 2007 / Hepatic venous pressure gradient predicts clinical decompensation in patients with compensated cirrhosis / Gastroenterology 133:481~488
de Franchis R / 2015 / Expanding consensus in portal hypertension:report of the Baveno VI Consensus Workshop: stratifying risk and individualizing care for portal hypertension / J Hepatol 63:743~752
Garcia-Tsao G / 2007 / Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis / Hepatology 46:922~938
Garcia-Tsao G / 2017 / Portal hypertensive bleeding in cirrhosis : risk stratification, diagnosis, and management : 2016 practice guidance by the American Association for the study of liver diseases / Hepatology 65:310~335
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