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논문 기본 정보

자료유형
학술저널
저자정보
Bruno Salomão Hirsch (University of Sao Paulo School of Medicine) Igor Braga Ribeiro (University of Sao Paulo School of Medicine) Mateus Pereira Funari (University of Sao Paulo School of Medicine) Diogo Turiani Hourneaux de Moura (University of Sao Paulo School of Medicine) Sergio Eiji Matuguma (University of Sao Paulo School of Medicine) Sergio A. Sánchez-Luna (Center for Advanced Endoscopy Allegheny Health Network Pittsburgh Pennsylvania) Fabio Catache Mancini (University of Sao Paulo School of Medicine) Guilherme Henrique Peixoto de Oliveira (University of Sao Paulo School of Medicine) Wanderley Marques Bernardo (University of Sao Paulo School of Medicine) Eduardo Guimarães Hourneaux de Moura (University of Sao Paulo School of Medicine)
저널정보
대한소화기내시경학회 Clinical Endoscopy Clinical Endoscopy 제54권 제5호
발행연도
2021.9
수록면
669 - 677 (9page)
DOI
10.5946/ce.2021.063

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Background/Aims: Argon plasma coagulation (APC) is the most commonly used endoscopic treatment for gastric antral vascularectasia (GAVE). Endoscopic band ligation (EBL) has emerged as an alternative therapy. Our goal was to evaluate the feasibility,efficacy, and safety of APC and EBL for the treatment of GAVE. This is the first systematic review that included only randomizedcontrolled trials (RCTs) on this topic. Methods: A comprehensive search was performed using electronic databases to identify RCTs comparing APC and EBL for thetreatment of GAVE following the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. Results: Four RCTs were included, with a total of 204 patients. EBL was related to higher endoscopic eradication rates risk difference[RD], 0.29; 95% confidence interval [CI] [0.14, 0.44]; I2=0%) and less bleeding recurrence than APC (RD, 0.29; 95% CI [0.15, 0.44];I2=0%). Patients treated with EBL required fewer blood transfusions (mean difference [MD], 1.49; 95% CI [0.28, 2.71]; I2=96%) andhospitalizations (MD, 0.29; 95% CI [0.19, 0.39]; I2=0%). The number of sessions required for the obliteration of lesions was higherwith APC. There was no difference in the incidence of adverse events. Conclusions: EBL is superior to APC in the treatment of GAVE in terms of endoscopic eradication rates, recurrence of bleeding, andtransfusion requirements.

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