지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.6
- 수록면
- 303 - 307 (5page)
- DOI
- https://doi.org/10.3904/kjm.2019.94.3.303
이용수
초록· 키워드
오류제보하기
Infliximab (IFX) is an anti-tumor necrosis factor (TNF) monoclonal antibody used to treat rheumatoid arthritis, ankylosing spondylitis, and Crohn’s disease. Rarely, anti-TNF-induced lupus (ATIL) may occur. ATIL differs from classical drug-induced lupus.
We report a 49-year-old woman who developed polyarthralgia after 2 years of IFX treatment for Crohn’s disease. Based on the autoantibody profiles, ATIL was diagnosed and low-dose glucocorticoid, hydroxychloroquine, and celecoxib were prescribed.
However, arthralgia and hemolytic anemia developed. Because the anti-dsDNA titers waxed and waned, she was switched to vedolizumab, a monoclonal antibody to the human lymphocyte α4β7 integrin. Six months after switching treatment, the arthralgia had improved and the anti-dsDNA antibody normalized. Here, we report a case of ATIL that resolved after switching from infliximab to vedolizumab.
목차
등록된 정보가 없습니다.
참고문헌 (10)
참고문헌 신청
박재준 / 2017 / 크론병 치료 가이드라인 개정판 / 대한소화기학회지 69(1):29~54
De Bandt M / 2005 / Systemic lupus erythematosus induced by anti-tumour necrosis factor alpha therapy : a French national survey / Arthritis Res Ther 7:R545~R551
Min-Jung Kang / 2006 / Etanercept-Induced Systemic Lupus Erythematosus in a Patient with Rheumatoid Arthritis / Journal of Korean Medical Science 21(5):946~949
Almoallim H / 2012 / Anti-tumor necrosis factor-α induced systemic lupus erythematosus / Open Rheumatol J 6:315~319
Costa MF / 2008 / Drug-induced lupus due to anti-tumor necrosis factor alpha agents / Semin Arthritis Rheum 37:381~387
De Bandt M / 2005 / Systemic lupus erythematosus induced by anti-tumour necrosis factor alpha therapy : a French national survey / Arthritis Res Ther 7:R545~R551
Min-Jung Kang / 2006 / Etanercept-Induced Systemic Lupus Erythematosus in a Patient with Rheumatoid Arthritis / Journal of Korean Medical Science 21(5):946~949
Almoallim H / 2012 / Anti-tumor necrosis factor-α induced systemic lupus erythematosus / Open Rheumatol J 6:315~319
Costa MF / 2008 / Drug-induced lupus due to anti-tumor necrosis factor alpha agents / Semin Arthritis Rheum 37:381~387
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