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논문 기본 정보

자료유형
학술저널
저자정보
Oliver Ristow (Department of Oral and Maxillofacial Surgery University Hospital Heidelberg Germany) Lena Hürtgen (Department of Oral and Maxillofacial Surgery University of Heidelberg Heidelberg Germany) Julius Moratin (Department of Oral and Maxillofacial Surgery University Hospital Heidelberg Germany) Maximilian Smielowski (Department of Oral and Maxillofacial Surgery University of Heidelberg Heidelberg Germany) Christian Freudlsperger (Department of Oral and Maxillofacial Surgery University Hospital Heidelberg Germany) Michael Engel (Department of Oral and Maxillofacial Surgery University Hospital Heidelberg Germany) Jürgen Hoffmann (Department of Oral and Maxillofacial Surgery University Hospital Heidelberg Germany) Thomas Rückschloß (Department of Oral and Maxillofacial Surgery University of Heidelberg Heidelberg Germany)
저널정보
대한구강악안면외과학회 대한구강악안면외과학회지 대한구강악안면외과학회지 제47권 제2호
발행연도
2021.4
수록면
99 - 111 (13page)
DOI
10.5125/jkaoms.2021.47.2.99

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Objectives: It is unclear whether the extent of intraoral mucosa defects in patients with medication-related osteonecrosis of the jaw indicates disease severity. Therefore, this study investigated whether mucosal lesions correlate with the true extent of osseous defects in stage I patients. Materials and Methods: Retrospectively, all patients with stage I medication-related osteonecrosis of the jaw who underwent surgical treatment between April 2018 and April 2019 were enrolled. Preoperatively, the extent of their mucosal lesions was measured in clinical evaluations, and patients were assigned to either the visible or the probeable bone group. Intraoperatively, the extent of necrosis was measured manually and with fluorescence. Results: Fifty-five patients (36 female, 19 male) with 86 lesions (46 visible bone, 40 probeable bone) were enrolled. Intraoperatively, the necrotic lesions were significantly larger (P<0.001) than the preoperative mucosal lesions in both groups. A significant (P<0.05) but very weak (R2<0.2) relationship was noted between the extent of the mucosal lesions and the necrotic bone area. Conclusion: Preoperative mucosal defects (visible or probeable) in patients with medication-related osteonecrosis of the jaw do not indicate the extent of bone necrosis or disease severity.
#Medication-related osteonecrosis of the jaw #Bisphosphonate-related osteonecrosis of the jaw #Antiresorptiva-related osteonecrosis of the jaw #Definition #Classification

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참고문헌 (41)

참고문헌 신청
Robert E Marx / 2003 / Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic / Journal of Oral and Maxillofacial Surgery 61(9):1115~1117 Crossref Massimo Viviano / 2017 / A case of bisphosphonate-related osteonecrosis of the jaw with a particularly unfavourable course: a case report / 대한구강악안면외과학회지 43(4):272~275 dbpia Aliya A. Khan / 2017 / Case-Based Review of Osteonecrosis of the Jaw (ONJ) and Application of the International Recommendations for Management From the International Task Force on ONJ / Journal of Clinical Densitometry 20(1):8~24 Crossref 김경민 / 2015 / Medication Related Osteonecrosis of the Jaw: 2015 Position Statement of the Korean Society for Bone and Mineral Research and the Korean Association of Oral and Maxillofacial Surgeons / 대한골대사학회지 22(4):151~165 google schola Schiegnitz E / 2017 / S3-leitlinie 007/091: antiresorptiva-assoziierte kiefernekrosen (AR-ONJ) / Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF) google schola

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