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Bisphosphonate-related osteonecrosis of the jaw in patients received long term treatment of oral bisphosphonate administration: Case reports
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논문 기본 정보

Type
Academic journal
Author
Journal
조선대학교 치의학연구원 Oral Biology Research Oral Biology Research 제40권 제1호 KCI Accredited Journals
Published
2016.1
Pages
43 - 48 (6page)

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Bisphosphonate-related osteonecrosis of the jaw in patients received long term treatment of oral bisphosphonate administration: Case reports
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Bisphosphonate-related osteonecrosis of the jaw (BRONJ) has been increasing every year, as the number of elders receiving bisphosphonate (BPs) therapy is increases. It is believed that BPs enhance the ORN by inhibition of the osteoclastic activity, but the exact mechanism is poorly understood. Patients who had received long-term oral BP therapy had a high recurrence rate of BRONJ. They needed to undergo segmental mandibulectomy and reconstruction, beyond getting just the conservative treatment, such as sequestrectomy. We present 2 such cases in this report. The patients had 7 years and 13 years of oral BP administration, respectively. These cases are being reported as we had good results after reconstruction, using reconstruction plate subsequent to segmental mandibulectomy.
#Bisphosphonate-associated osteonecrosis of the jaw #Jaw disease #Spontaneous fracture

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References (17)

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Sigua-Rodriguez EA / 2014 / Bisphosphonate-Related Osteonecrosis of the Jaw : A Review of the Literature / Int J Dent 2014:192320 google schola Vescovi P / 2014 / Conservative surgical management of stage I bisphosphonate-related osteonecrosis of the jaw / Int J Dent 2014:107690 google schola Yoshiga D / 2014 / Prognosis factors in the treatment of bisphosphonate-related osteonecrosis of the jaw - Prognostic factors in the treatment of BRONJ / J Clin Exp Dent 6:e22~e28 google schola Lemound J / 2012 / Bisphosphonate-associated osteonecrosis of the mandible : reliable soft tissue reconstruction using a local myofascial flap / Clin Oral Investig 16:1143~1152 google schola Kumar V / 2014 / Nitrogen containing bisphosphonates associated osteonecrosis of the jaws : A review for past 10 year literature / Dent Res J(Isfahan) 11:147~153 google schola

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