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자료유형
학술저널
저자정보
윤진아 (부산대학교) 신용일 (부산대학교) 김덕용 (연세대학교) Min Kyun Sohn (Department of Rehabilitation Medicine, Chungnam National University School of Medicine, Daejeon, Ko) Jongmin Lee (Department of Rehabilitation Medicine, Konkuk University School of Medicine, Seoul, Korea) Sam-Gyu Lee (Department of Physical and Rehabilitation Medicine, Chonnam National University Medical School, Gwa) Yang-Soo Lee (Department of Rehabilitation Medicine, Kyungpook National University College of Medicine, Daegu, Ko) Eun Young Han (Department of Rehabilitation Medicine, Jeju National University Hospital, Jeju University College o) Min Cheol Joo (Department of Rehabilitation Medicine, Wonkwang University School of Medicine, Iksan, Korea) Gyung-Jae Oh (Department of Rehabilitation Medicine Wonkwang University School of Medicine Iksan Korea) Minsu Park (Pusan National University Hospital) 장원혁 (삼성서울병원) Yun-Hee Kim (Sungkyunkwan University School of Medicine)
저널정보
대한재활의학회 Annals of Rehabilitation Medicine Annals of Rehabilitation Medicine 제45권 제5호
발행연도
2021.10
수록면
359 - 367 (9page)
DOI
10.5535/arm.21124

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Objective To investigate long-term and serial functional outcomes in ischemic stroke patients without diabetes with post-stroke hyperglycemia. Methods The Korean Stroke Cohort for Functioning and Rehabilitation (KOSCO) is a large, multi-center, prospective cohort study of stroke patients admitted to participating hospitals in nine areas of Korea. From KOSCO, ischemic stroke patients without diabetes were recruited and divided into two groups: patients without diabetes without (n=779) and with post-stroke hyperglycemia (n=223). Post-stroke hyperglycemia was defined as a glucose level >8 mmol/L. Functional assessments were performed 7 days and 3, 6, and 12 months after stroke onset. Results There were no significant differences in baseline characteristics between the groups, except in the age of onset and smoking. Analysis of the linear correlation between the initial National Institutes of Health Stroke Scale (NIHSS) score and glucose level showed no significant difference. Among our functional assessments, NIHSS, Fugl-Meyer Assessment (affected side), Functional Ambulatory Category, modified Rankin Scale, and Korean Mini-Mental State Examination (K-MMSE) showed statistically significant improvements in each group. All functional improvements except K-MMSE were significantly higher in patients without post-stroke hyperglycemia at 7 days and 3, 6, and 12 months. Conclusion The glucose level of ischemic stroke patients without diabetes had no significant correlation with the initial NIHSS score. The long-term effects of stress hyperglycemia showed worse functional outcomes in ischemic stroke patients without diabetes with post-stroke hyperglycemia.

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