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논문 기본 정보

자료유형
학술저널
저자정보
Lee Kanghoon (Department of Thoracic and Cardiovascular Surgery International St. Mary's Hospital Catholic Kwando) Kim Hyeong Ryul (Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College o) Park Seung-Il (Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College o) Kim Dong Kwan (Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College o) Kim Yong-Hee (Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College o) Choi Sehoon (Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College o) Lee Geun Dong (Department of Thoracic and Cardiovascular Surgery Asan Medical Center University of Ulsan College o)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.36 No.43
발행연도
2021.11
수록면
1 - 9 (9page)
DOI
10.3346/jkms.2021.36.e266

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Background: This retrospective study investigated the natural course of synchronous groundglass nodules (GGNs) that remained after curative resection for non-small-cell lung cancer (NSCLC). Methods: Prospectively collected retrospective data were reviewed concerning 2,276 patients who underwent curative resection for NSCLC between 2008 and 2017. High-resolution computed tomography or thin-section computed tomography data of 82 patients were included in the study. Growth in size was considered the most valuable outcome, and patients were grouped according to GGN size change. Patient demographic data (e.g., age, sex, and smoking history), perioperative data (e.g., GGN characteristics, histopathology and pathological stage of the resected tumours), and other medical history were evaluated in a risk factor analysis concerning GGN size change. Results: The median duration of follow-up was 36.0 months (interquartile range, 23.0?59.3 months). GGN size decreased in 6 patients (7.3%), was stationary in 43 patients (52.4%), and increased in 33 patients (40.2%). In univariate analysis, male sex, the GGN size on initial CT, part-solid GGN and smoking history (≥ 10 pack-years) were significant risk factors. Among them, multivariate analysis revealed that lager GGN size, part-solid GGN and smoking history were independent risk factors. Conclusion: During follow-up, 40.2% of GGNs increased in size, emphasising that patients with larger GGNs, part-solid GGN or with a smoking history should be observed.
#Ground-Glass Nodule #Lung Cancer #Computed Tomography

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참고문헌 (25)

참고문헌 신청
National Lung Screening Trial Research Team / 2011 / Reduced lung-cancer mortality with low-dose computed tomographic screening / N Engl J Med 365(5):395~409 google schola Pastorino U / 2019 / Prolonged lung cancer screening reduced 10-year mortality in the MILD trial : new confirmation of lung cancer screening efficacy / Ann Oncol 30(10):1672 google schola De Koning H / 2018 / PL02. 05 Effects of volume CT lung cancer screening : mortality results of the NELSON randomised-controlled population based trial / J Thorac Oncol 13(10):S185 google schola Henschke CI / 2006 / CT screening for lung cancer : prevalence and incidence of mediastinal masses / Radiology 239(2):586~590 google schola Takx RA / 2015 / Quantification of coronary artery calcium in nongated CT to predict cardiovascular events in male lung cancer screening participants : results of the NELSON study / J Cardiovasc Comput Tomogr 9(1):50~57 google schola

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