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논문 기본 정보

자료유형
학술저널
저자정보
Min Jin-Young (Department of Otolaryngology-Head and Neck Surgery School of Medicine Kyung Hee University Seoul Ko) Kim Yong Min (Department of Otolaryngology-Head and Neck Surgery School of Medicine Chungnam National University) Dae Woo Kim (Seoul Metropolitan Government Seoul National University Boramae Medical Center) Kim Jeong-Whun (Department of Otolaryngology-Head and Neck Surgery Seoul National University College of Medicine Se) Kim Jin Kook (Department of Otolaryngology-Head and Neck Surgery School of Medicine Konkuk University Seoul Korea) Mo Ji-Hun (Department of Otolaryngology-Head and Neck Surgery School of Medicine Dankook University College of) Shin Jae-Min (Department of Otolaryngology-Head and Neck Surgery School of Medicine Korea University Seoul Korea.) Cho Kyu-Sup (Department of Otolaryngology-Head and Neck Surgery Pusan National University School of Medicine Bus) Kwak Sanggyu (Department of Medical Statistics School of Medicine Catholic University of Daegu Daegu Korea.) Shin Seung-Heon (Department of Otolaryngology-Head and Neck Surgery School of Medicine Catholic University of Daegu)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.36 No.40
발행연도
2021.10
수록면
1 - 11 (11page)
DOI
10.3346/jkms.2021.36.e264

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Background: Endoscopic sinus surgery (ESS) is the mainstay treatment for refractory chronic rhinosinusitis (CRS). Since various factors may contribute to the surgical outcome, it is challenging for physicians to predict surgical outcomes. The aim of study was to analyze the prognostic factors of postoperative outcomes and to establish the prediction model with the risk factors that impact the postoperative outcomes. Methods: Medical records of CRS patients who underwent ESS at 9 institutions in 2005, 2010, and 2016 were retrospectively reviewed. We classified the patients into 2 groups based on postoperative objective endoscopic outcomes. Demographics, nose-specific symptoms, olfactory function, eosinophil counts in blood (EoB) and nasal tissue (EoT), and LundMackay CT score (LMS) were collected. Univariate and multivariate analyses were performed and established a prediction equation for postoperative endoscopic objective outcomes. Results: In total (n = 1,249), 27.0% were not satisfied under postoperative endoscopic examination. Of 10 variables, LMS (> 5), sinus dominancy (maxillary sinus and ethmoid sinus), EoB (> 210), and EoT (> 100) were statistically significant in univariate analysis (P < 0.05, all). In multivariate analysis, EoT (> 100) and LMS (> 5) were significantly associated with poor postoperative outcome. Furthermore, 5 significant variables were employed to establish the risk model of postoperative outcomes and P (the value of prediction probability) = 1 / (1 + exp [?0.392 + 1.088 × EoT (> 100) + 0.123 × mean LMS (> 5) ? 0.366 × sinus dominancy (maxillary) + 0.064 × sinus dominancy (similar) + 0.200 × EoB (4%) + 0.344 × EoB (> 210)] was developed. Conclusion: Tissue eosinophil count and radiographic severity predispose to a poorer outcome of ESS and the risk model established may be helpful to predict postoperative outcomes of ESS.

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