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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국약제학회 Journal of Pharmaceutical Investigation Journal of Pharmaceutical Investigation 제48권 제3호
- 발행연도
- 2018.5
- 수록면
- 243 - 250 (8page)
- DOI
- 10.1007/s40005-017-0303-2
이용수
초록· 키워드
오류제보하기
In this study, we investigated the effect of fish scale collage (FSC) on type I procollagen expression in cultured human dermal fibroblasts using real-time polymerase chain reaction and ELISA, under normal and UV exposure condition. Also, FSC encapsulated negatively surface modified nanoliposome ( NLsurf mod) was fabricated, and the physicochemical characteristics of the liposomes and skin permeation properties were evaluated. FSC increased type I procollagen mRNA and protein expression in human dermal fibroblasts. The mean particle size, zeta potential value and encapsulation efficiency of the NLsurf mod were about 175 nm, ?44 mV and 11%, respectively. The skin localization effect was enhanced by NLsurf mod. Conclusively, FSC is able to elevate the type I procollagen expression in human dermal fibroblasts and FSC-loaded NLsurf mod would be a good candidate for the topical delivery of FSC.
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등록된 정보가 없습니다.
참고문헌 (40)
참고문헌 신청
Badiee A / 2009 / The role of liposome charge on immune response generated in BALB/c mice immunized with recombinant major surface glycoprotein of Leishmania (rgp63) / Exp Parasitol 121:362~369
Santosh Bashyal / 2015 / Delivery of biopharmaceuticals using combination of liposome and iontophoresis: a review / Journal of Pharmaceutical Investigation 45(7):611~624
Betz G / 2001 / Interaction of liposome formulations with human skin in vitro / Int J Pharm 229:117~129
Biruss B / 2007 / Comparative characterization of the physicochemical behavior and skin permeation of extruded DPPC liposomes modified by selected additives / J Pharm Sci 96:2171~2176
Chai HJ / 2010 / Effects of sizes and conformations of fish-scale collagen peptides on facial skin qualities and transdermal penetration efficiency / J BioMed Res 2010:1~9
Santosh Bashyal / 2015 / Delivery of biopharmaceuticals using combination of liposome and iontophoresis: a review / Journal of Pharmaceutical Investigation 45(7):611~624
Betz G / 2001 / Interaction of liposome formulations with human skin in vitro / Int J Pharm 229:117~129
Biruss B / 2007 / Comparative characterization of the physicochemical behavior and skin permeation of extruded DPPC liposomes modified by selected additives / J Pharm Sci 96:2171~2176
Chai HJ / 2010 / Effects of sizes and conformations of fish-scale collagen peptides on facial skin qualities and transdermal penetration efficiency / J BioMed Res 2010:1~9
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