지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.9
- 수록면
- 1 - 9 (9page)
- DOI
- 10.1038/s12276-021-00679-8
이용수
초록· 키워드
오류제보하기
Retinoic acid receptor-related orphan receptor-α (RORα) is a member of the orphan nuclear receptor family and functions as a transcriptional activator in response to circadian changes. Circadian rhythms are complex cellular mechanisms regulating diverse metabolic, inflammatory, and tumorigenic gene expression pathways that govern cyclic cellular physiology. Disruption of circadian regulators, including RORα, plays a critical role in tumorigenesis and facilitates the development of inflammatory hallmarks. Although RORα contributes to overall fitness among anticancer, anti-inflammatory, lipid homeostasis, and circadian clock mechanisms, the molecular mechanisms underlying the mode of transcriptional regulation by RORα remain unclear. Nonetheless, RORα has important implications for pharmacological prevention of cancer, inflammation, and metabolic diseases, and understanding context-dependent RORα regulation will provide an innovative approach for unraveling the functional link between cancer metabolism and rhythm changes.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Alleviation of imiquimod-induced psoriasis-like symptoms in Rorα-deficient mouse skin
BMB Reports
2023 .05
-
ROR Model을 이용한 원격 사용자 인증 방식의 안전성 분석
한국통신학회 학술대회논문집
2017 .11
-
Roles of circadian clocks in cancer pathogenesis and treatment
Experimental and Molecular Medicine
2021 .10
-
Dynamic Circadian Regulation and Modulator of Clock Genes in Skin Cells
한국생물공학회 학술대회
2021 .10
-
Circadian Rhythm and Human Health: Researches of BCA2-RLRC (Biological Clock-based Anti-Aging Convergence Regional Leading Research Center of NRF, Korea)
한국생물공학회 학술대회
2022 .09
-
Circadian Lighting
조명·전기설비
2019 .11
-
Circadian Lighting 개발을 위한 기초 연구
한국조명·전기설비학회 학술대회논문집
2015 .11
-
Mesenchymal stem cell-derived extracellular vesicles subvert Th17 cells by destabilizing RORγt through posttranslational modification
Experimental and Molecular Medicine
2023 .03
-
Sleep, circadian rhythms, and the pathogenesis of Alzheimer Disease
Experimental and Molecular Medicine
2015 .01
-
Programming effects of maternal stress on the circadian system of adult offspring
Experimental and Molecular Medicine
2020 .01
-
주광 색온도에 따른 Circadian Action Factor 값 예측 모델 개발
한국조명·전기설비학회 학술대회논문집
2017 .05
-
Diversification of the molecular clockwork for tissue-specific function: insight from a novel Drosophila Clock mutant homologous to a mouse Clock allele
BMB Reports
2016 .01
-
Soluble receptors in cancer: mechanisms, clinical significance, and therapeutic strategies
Experimental and Molecular Medicine
2024 .01
-
항공기 탑재 장비의 주파수 회피 및 진동 저감 절차에 대한 연구
한국정밀공학회 학술발표대회 논문집
2019 .05
-
A novel targeting material to receptors of cancer cells
한국생물공학회 학술대회
2018 .04
-
Regulation of Skin Clock Genes by AK-extract in HaCaT Keratinocyte
한국생물공학회 학술대회
2020 .06
-
건축계획에서 건강과 웰빙을 위한 주광설계 요소분석 - 생체 시스템과 시각적 쾌적함을 중심으로 -
대한건축학회논문집
2020 .12
-
건축환경에서 생체리듬을 고려한 인간중심조명 디자인에 관한 문헌고찰
대한건축학회논문집
2022 .02
-
The end effector of circadian heart rate variation: the sinoatrial node pacemaker cell
BMB Reports
2015 .01
-
The circadian rhythm in intervertebral disc degeneration: an autophagy connection
Experimental and Molecular Medicine
2020 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0