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논문 기본 정보

자료유형
학술저널
저자정보
Wei-Yi Lei (Department of Medicine Hualien Tzu Chi Hospital Buddhist Tzu Chi Medical Foundation and Tzu Chi Uni) Shu-Wei Liang (Department of Medicine Hualien Tzu Chi Hospital Buddhist Tzu Chi Medical Foundation and Tzu Chi Uni) Taher Omari (College of Medicine and Public Health Flinders University Adelaide Australia) Wei-Chuan Chang (Department of Medical Research Hualien Tzu Chi Hospital Buddhist Tzu Chi Medical Foundation Hualien) Ming-Wun Wong (Department of Medicine Hualien Tzu Chi Hospital Buddhist Tzu Chi Medical Foundation and Tzu Chi Uni) Jui-Sheng Hung (Department of Medicine Hualien Tzu Chi Hospital Buddhist Tzu Chi Medical Foundation and Tzu Chi Uni) Chih-Hsun Yi (Department of Medicine Hualien Tzu Chi Hospital Buddhist Tzu Chi Medical Foundation and Tzu Chi Uni) Tso-Tsai Liu (Department of Medicine Hualien Tzu Chi Hospital Buddhist Tzu Chi Medical Foundation and Tzu Chi Uni) Lin Lin (Department of Medicine Hualien Tzu Chi Hospital Buddhist Tzu Chi Medical Foundation and Tzu Chi Uni) C Prakash Gyawali (Division of Gastroenterology Washington University School of Medicine St Louis MO USA) Chien-Lin Chen (Department of Medicine Hualien Tzu Chi Hospital Buddhist Tzu Chi Medical Foundation and Tzu Chi Uni)
저널정보
대한소화관운동학회(현 대한소화기능성질환.운동학회) Journal of Neurogastroenterology and Motility (JNM) Journal of Neurogastroenterology and Motility (JNM) Vol.28 No.4
발행연도
2022.10
수록면
589 - 598 (10page)
DOI
10.5056/jnm21189

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"Background/Aims Straight leg raise (SLR) can be utilized to evaluate the integrity of the esophagogastric junction during high-resolution manometry (HRM). We aim to assess the value of transient hiatal separation during SLR in symptomatic reflux patients. Methods Consecutive reflux patients undergoing esophageal HRM and pH monitoring were included. Transient hiatal separation was defined by a ≥ 1 cm separation between the lower esophageal sphincter and crural diaphragm during SLR. We compared esophageal motor patterns and reflux monitoring parameters between patients with normal, transiently abnormal and consistently abnormal esophagogastric junction morphology during SLR. Results Of 85 (56.3% female, mean age: 46.7 ± 12.3 years) completed SLR, esophagogastric junction morphology was normal in 31 (36.5%), transient hiatal separation in 19 (22.3%), and consistently hiatal hernia in 35 (41.2%). The values of total acid exposure time (P = 0.016), longest acid reflux episodes (P = 0.024), and DeMeester scores (P = 0.016) were higher in hiatal hernia compared to patients with non-transient hiatal separation, but there were no differences between those with and without transient hiatal separation. Within ineffective esophageal motility, the presence of transient hiatal separation during SLR significantly associated with a higher total acid exposure time (P = 0.014), higher DeMeester scores (P = 0.019), higher total acid reflux events (P = 0.037), and higher longest acid reflux episodes (P = 0.006). Conclusion Our work suggests that SLR may have value as a provocative test during HRM, and future outcome studies are warranted to elucidate the clinical relevance of motor abnormalities depicted from SLR."

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