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논문 기본 정보

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학술저널
저자정보
Jandos Amankulov (Department of Radiology and Nuclear Medicine, Kazakh Institute of Oncology and Radiology, Almaty, K) Dilyara Kaidarova (Department of Medical Oncology, Kazakh Institute of Oncology and Radiology, Almaty, Kazakhstan) Zhamilya Zholdybay (Department of Visual Diagnostics, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhst) Marianna Zagurovskaya (Department of Radiology Medical College at the University of Kentucky Lexington KY USA) Nurlan Baltabekov (Department of Medical Oncology, Kazakh Institute of Oncology and Radiology, Almaty, Kazakhstan) Madina Gabdullina (Department of Radiology and Nuclear Medicine, Kazakh Institute of Oncology and Radiology, Almaty, K) Akmaral Ainakulova (Department of Radiology and Nuclear Medicine, Kazakh Institute of Oncology and Radiology, Almaty, K) Dias Toleshbayev (Department of Radiology and Nuclear Medicine, Kazakh Institute of Oncology and Radiology, Almaty, K) Alexandra Panina (Department of Radiology and Nuclear Medicine, Kazakh Institute of Oncology and Radiology, Almaty, K) Elvira Satbayeva (Center of Morphological Diagnostics Kazakh Institute of Oncology and Radiology Almaty Kazakhstan) Zhansaya Kalieva (Department of Endoscopy Kazakh Institute of Oncology and Radiology Almaty Kazakhstan)
저널정보
대한소화기내시경학회 Clinical Endoscopy Clinical Endoscopy 제55권 제1호
발행연도
2022.1
수록면
101 - 112 (12page)
DOI
10.5946/ce.2021.066

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Background/Aims: The aim of our study was to determine the efficacy of computed tomography colonography (CTC) in screeningfor colorectal cancer (CRC). Methods: A total of 612 females and 588 males aged 45 to 75 years were enrolled in CTC screening. CTC was performed followingstandard bowel preparation and colonic insufflation with carbon dioxide. The main outcomes were the detection rate of CRC andadvanced adenoma (AA), prevalence of colorectal lesions in relation to socio-demographic and health factors, and overall diagnosticperformance of CTC. Results: Overall, 56.5% of the 1,200 invited subjects underwent CTC screening. The sensitivity for CRC and AA was 0.89 and0.97, respectively, while the specificity was 0.71 and 0.99, respectively. The prevalence of CRC and AA was 3.0% (18/593) and 7.1%(42/593), respectively, with the highest CRC prevalence in the 66-75 age group (≥12 times; odds ratio [OR], 12.11; 95% confidenceinterval [CI], 4.45-32.92). CRC and AA prevalence were inversely correlated with Asian descent, physical activity, and negative fecalimmunochemical test results (OR=0.43; 95% CI, 0.22-0.83; OR=0.16; 95% CI, 0.04-0.68; OR=0.5; 95% CI, 0.07-3.85, respectively). Conclusions: Our study revealed high accuracy of CTC in diagnosing colonic neoplasms, good compliance with CTC screening, andhigh detection rate of CRC.

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