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논문 기본 정보

자료유형
학술저널
저자정보
Lee Yoonha (Department of Pediatrics Seoul National University Bundang Hospital Seongnam Korea.Department of Pe) Kim Minseung (Department of Pediatrics Seoul National University Bundang Hospital Seongnam Korea.) Oh Kyeongeun (Department of Pediatrics Korea University Ansan Hospital Ansan Korea.) Kang Eungu (Department of Pediatrics Korea University Ansan Hospital Ansan Korea.) Rhie Young-Jun (Department of Pediatrics Korea University Ansan Hospital Ansan Korea.) Lee Jieun (Department of Pediatrics Inje University Ilsan Paik Hospital Goyang Korea.) Hong Yong Hee (Department of Pediatrics Soonchunhyang University Bucheon Hospital Soonchunhyang University College) Shin Young-Lim (Department of Pediatrics Soonchunhyang University Bucheon Hospital Soonchunhyang University College) Kim Jae Hyun (Department of Pediatrics Seoul National University Bundang Hospital Seongnam Korea.Department of Pe)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.37 No.22
발행연도
2022.6
수록면
1 - 13 (13page)
DOI
10.3346/jkms.2022.37.e176

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Background: Hospital visitation has become challenging during the coronavirus disease 2019 pandemic because of quarantine measures and fear of infection. Consequently, newly diagnosed patients may present with more severe diseases during the pandemic. The present study analyzed the differences in the initial clinical presentations of newly diagnosed patients with type 1 diabetes (T1D) and type 2 diabetes (T2D), comparing pre-pandemic and pandemic periods. Methods: Newly diagnosed patients with T1D or T2D and aged < 18 years during 2018?2020 were included in the study. Data were collected retrospectively from four academic centers in Gyeonggi-do, South Korea. Initial clinical data were compared between the pre-pandemic (2018?2019) and pandemic (2020) periods. Results: In the pre-pandemic and pandemic periods, 99 patients (41 T1D and 58 T2D patients) and 84 patients (51 T1D and 33 T2D patients) were identified, respectively. During the pandemic, the proportion of diabetic ketoacidosis (DKA) cases increased compared to the pre-pandemic period (21.2% during 2018?2019 vs. 38.1% in 2020; P = 0.012). In the prepandemic and pandemic periods, initial pH was 7.32 ± 0.14 and 7.27 ± 0.15, respectively (P = 0.040), and HbA1c values were 11.18 ± 2.46% and 12.42 ± 2.87%, respectively (P = 0.002). During the pandemic, there was an increased risk of DKA in patients with T1D (odds ratio, 2.42; 95% confidence interval, 1.04?5.62; P = 0.040). Conclusion: During the pandemic, the proportion of DKA in newly diagnosed patients with T1D increased and clinical parameters showed a deteriorating pattern. Increased awareness of pediatric diabetes, especially DKA, could facilitate visit to the hospital for an early diagnosis; thus, reducing the number of DKA cases during the pandemic era.

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