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논문 기본 정보

자료유형
학술저널
저자정보
Kim Min Jeong (School of Food Science and Biotechnology Kyungpook National University Daegu 41566 Republic of Kore) Istianah Nur (School of Food Science and Biotechnology Kyungpook National University Daegu 41566 Republic of Kore) So Bo Ram (School of Food Science and Biotechnology Kyungpook National University Daegu 41566 Republic of Kore) Kang Hye Jee (School of Food Science and Biotechnology Kyungpook National University Daegu 41566 Republic of Kore) Woo Min Jeong (School of Food Science and Biotechnology Kyungpook National University Daegu 41566 Republic of Kore) Park Su Jin (Research Center Honest Co. Ltd. 102 Maeyeo-ro Dong-gu Daegu 41064 Republic of Korea) Kim Hyun Jeong (Research Center Honest Co. Ltd. 102 Maeyeo-ro Dong-gu Daegu 41064 Republic of Korea) 정영훈 (경북대학교) 정성근 (경북대학교)
저널정보
한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제32권 제12호
발행연도
2022.12
수록면
1,589 - 1,598 (10page)
DOI
10.4014/jmb.2210.10009

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Microfibrillated cellulose (MFC) is a valuable material with wide industrial applications, particularly for the food and cosmetics industries, owing to its excellent physiochemical properties. Here, we prepared high-solid microfibrillated cellulose (HMFC) from the centrifugation of Gelidium amansiiderived MFC right after fibrillation. Dispersion properties, morphology, and structural changes were monitored during processing. HMFC has a five-fold higher solid concentration than MFC without significant changes to dispersion properties. SEM images and FTIR spectra of HMFC revealed a stable surface and structure against centrifugal forces. HMFC exhibited 2,2′-azino-bis (3-ethylbenzothiazoline6-sulfonic acid) (ABTS) radical scavenging activity, although it could not scavenge 2,2-diphenyl-1- picrylhydrazyl (DPPH). Moreover, HMFC inhibited the generation of LPS-induced excessive nitrite and radial oxygen species in murine macrophage RAW264.7 cells. Additionally, HMFC suppressed LPS-induced Keap-1 expression in the cytosol but did not alter iNOS expression. HMFC also attenuated the UVB-induced phosphorylation of p38, c-Jun N-terminal kinase (JNK) 1/2, and extracellular-signal-regulated kinase (ERK) 1/2, as well as the phosphorylation of c-Jun in the immortalized human skin keratinocyte HaCaT cells. Therefore, the application of centrifugation is suitable for producing high-solid MFC as a candidate material for anti-inflammatory and antioxidative marine cosmeceuticals.

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