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논문 기본 정보

자료유형
학술저널
저자정보
Jeon Hyeon Ji (School of Food Science and Biotechnology Kyungpook National University Daegu 41566 Republic of Kore) Ban O-Hyun (School of Food Science and Biotechnology Kyungpook National University Daegu 41566 Republic of Kore) Bang Won Yeong (Ildong Bioscience Pyeongtaek-si Gyeonggi-do 17957 Republic of Korea) Yang Jungwoo (Ildong Bioscience Pyeongtaek-si Gyeonggi-do 17957 Republic of Korea) 정영훈 (경북대학교)
저널정보
한국미생물생명공학회 한국미생물·생명공학회지 한국미생물·생명공학회지 제50권 제4호
발행연도
2022.12
수록면
465 - 476 (12page)
DOI
10.48022/mbl.2210.10013

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The importance of beneficial microorganisms, particularly probiotics, that coexist in the human body, is being increasingly recognized. Probiotics are representative health functional foods that provide health benefits to humans through the production of various metabolites, including short-chain fatty acids. However, the health benefits are strain-specific, and the use of each probiotic strain should follow guidelines that assure its safety. Accurate identification of the strain should be managed through genetic and phenotypic analyses of the strain. Besides, the functionality of probiotics should be disclosed in vitro and in vivo so that they can be used as legal functional ingredients (i.e., individual standards). In this review, we deal with the guidelines, including the technical factors related to probiotic strains. The common health effects of probiotic strains include proliferation of beneficial bacteria, control of harmful bacteria, and facilitation of bowel activities. Probiotics with various functionalities (e.g., body fat and cholesterol reduction, vaginal health, and improvement of skin’s immune system) have been investigated as “individual standards of raw materials for health functional foods” provided by MFDS. In the future, various biotechnologies including synthetic biology can be applied to produce customized probiotics to improve human health.

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