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논문 기본 정보

자료유형
학술저널
저자정보
So Jeong Yoon (Sungkyunkwan University School of Medicine) Wooil Kwon (Seoul National University College of Medicine) Ok Joo Lee (Sungkyunkwan University School of Medicine) Ji Hye Jung (Sungkyunkwan University School of Medicine) Yong Chan Shin (Inje University College of Medicine) Chang-Sup Lim (Seoul National University College of Medicine) Hongbeom Kim (Seoul National University College of Medicine) Jin-Young Jang (Seoul National University College of Medicine) Sang Hyun Shin (Sungkyunkwan University School of Medicine) Jin Seok Heo (Sungkyunkwan University School of Medicine) In Woong Han (Sungkyunkwan University School of Medicine)
저널정보
대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.102 No.3
발행연도
2022.3
수록면
147 - 152 (6page)

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Purpose: Postoperative pancreatic fistula (POPF) is a life-threatening complication following pancreatoduodenectomy (PD). We previously developed nomogram- and artificial intelligence (AI)-based risk prediction platforms for POPF after PD. This study aims to externally validate these platforms.
Methods: Between January 2007 and December 2016, a total of 1,576 patients who underwent PD in Seoul National University Hospital, Ilsan Paik Hospital, and Boramae Medical Center were retrospectively reviewed. The individual risk scores for POPF were calculated using each platform by Samsung Medical Center. The predictive ability was evaluated using a receiver operating characteristic curve and the area under the curve (AUC). The optimal predictive value was obtained via backward elimination in accordance with the results from the AI development process.
Results: The AUC of the nomogram after external validation was 0.679 (P < 0.001). The values of AUC after backward elimination in the AI model varied from 0.585 to 0.672. A total of 13 risk factors represented the maximal AUC of 0.672 (P < 0.001).
Conclusion: We performed external validation of previously developed platforms for predicting POPF. Further research is needed to investigate other potential risk factors and thereby improve the predictability of the platform.

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INTRODUCTION
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