지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.4
- 수록면
- 169 - 174 (6page)
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초록· 키워드
오류제보하기
Muscle vibration measurement has long been an unique scientific study, in general, and the directreaction of animals to feel pain (algesia), either from vascular or muscle contraction, is a complexperceptual experience. Thus this paper proposes a way to measure animal algesia quantitatively, bymeasuring the changes in muscle vibration due to a pinprick on the surface of the skin of a Spodopteralitura larva. Using the laser optical triangulation measurement principle, along with a CMOS image sensor,linear laser, software analysis, and other tools, we quantify the subtle object point displacement, with aprecision of up to 10 μm, for our chosen Spodoptera litura larva animal model, in which it is not easyto identify the tiny changes in muscle contraction dynamics with the naked eye. We inject differentconcentrations of formalin reagent (empty needle, 12% formalin, and 37% formalin) to obtain a varietyof different muscle vibration frequencies as the experimental results. Because of the high concentrationsof reagent applied, we see a high frequency shift of muscle vibration, which can be presented as painindices, so that the algesia can be quantified
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
E. H. Hofmeister / 2007 / Sample size and statistical power in the small-animal analgesia literature / Journal of Small Animal Practice 48:76~79
A. Tjølsen / 1997 / Animal models of analgesia / The Pharmacology of Pain 130:1~20
L. F. Vendruscolo / 2004 / Synergistic interaction between mazindol, an anorectic drug, and swim-stress on analgesic responses in the formalin test in mice / Neurosci. Lett 355:13~16
S. Louisa / 2010 / Considerations for prospective studies in animal analgesia / Veterinary Anaesthesia and Analgesia 37:303~305
I. Hiroki / 2006 / Stress-induced hyperalgesia: Animal models and putative mechanisms / Frontiers in Bioscience 11:2179~2192
A. Tjølsen / 1997 / Animal models of analgesia / The Pharmacology of Pain 130:1~20
L. F. Vendruscolo / 2004 / Synergistic interaction between mazindol, an anorectic drug, and swim-stress on analgesic responses in the formalin test in mice / Neurosci. Lett 355:13~16
S. Louisa / 2010 / Considerations for prospective studies in animal analgesia / Veterinary Anaesthesia and Analgesia 37:303~305
I. Hiroki / 2006 / Stress-induced hyperalgesia: Animal models and putative mechanisms / Frontiers in Bioscience 11:2179~2192
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