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논문 기본 정보

자료유형
학술저널
저자정보
Hyun Jun Lee (Sahmyook University) Sang Back Kim (Kolmar Korea) Kyung Jun Boo (Konkuk University) Darlene Mae Ortiz (Sahmyook University) Leandro Val Sayson (Sahmyook University) Raly James Perez Custodio (Jeonbuk National University) Jae Hoon Cheong (Jeonbuk National University) Seul Ki Kim (Kolmar BNH) Mikyung Kim (Sahmyook University) Hee Jin Kim (Sahmyook University)
저널정보
한국생약학회 Natural Product Sciences Natural Product Sciences Vol.28 No.2
발행연도
2022.6
수록면
68 - 74 (7page)
DOI
10.20307/nps.2022.28.2.68

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HemoHIM was used as a Korean traditional medicine for anti-inflammatory and antioxidant effects. However, there is no study on the effect of HemoHIM on fatigue. We examined the potential use of HemoHIM to determine whether it can induce anti-fatigue effects. Mice were administered with HemoHIM and VEH for 14 days. On the last day of treatment, mice were subjected to behavioral tests. Subsequently, their plasma and muscle were collected after the treadmill test to measure lactate, lactate dehydrogenase (LDH), ammonia, corticosterone, glycogen, and creatine kinase (CK). We found that HemoHIM moderately increased the running time (s) in the treadmill and mobility duration in the cold swimming tests. In addition, the VEH group showed a significant increase in lactate, LDH, and corticosterone levels in the plasma compared to the group that did not perform the test. However, this was moderately reduced in HemoHIM treatment. Moreover, the HemoHIMtreated group showed significant differences in LDH and glycogen levels, and showed significantly different CK levels in the muscle. HemoHIM is considered to be effective in improving fatigue, given the duration of cold swimming or running time on a treadmill. Also, HemoHIM treatment resulted in reduced concentrations of blood and muscle parameter analysis.

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Abstract
Introduction
Experimental
Result and Discussion
Result and Discussion
References

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