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논문 기본 정보

자료유형
학술저널
저자정보
Juree Kim (Chung-Ang University) Quynh Nhu Nguyen (Gachon University) Hanna Shin (National Institute of Forest Science) Ki Sung Kang (Gachon University) Sanghyun Lee (Chung-Ang University)
저널정보
한국생약학회 생약학회지(Korean Journal of Pharmacognosy) 생약학회지 제52권 제4호
발행연도
2021.12
수록면
257 - 266 (10page)

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초록· 키워드

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This study evaluated several in vitro activities including the preliminary assessment of the anti-cancer, anti-inflammatory, and anti-diabetic effects of tree sprout extracts. Chlorogenic, caffeic, and p-coumaric acid contents in tree sprouts were analyzed using high-performance liquid chromatography and an ultraviolet detector. Among the studied tree sprout extracts, the ethanol (EtOH) extract of Rhus verniciflua exhibited the most potent anti-cancer effect by suppressing the cell viability of a human gastric adenocarcinoma cell line, with an IC50 of 7.06 ㎍/mL. The EtOH extract of Morus alba (MAB) inhibited the secretion of nitric oxide (NO) at a concentration of 100 ㎍/mL, with an IC50 of 83.44 ㎍/mL. Moreover, the EtOH extract of Securinega suffruticosa inhibited NO secretion with the lowest IC50 of 54.42 ㎍/mL. The EtOH extract of Fraxinus mandschurica was the only extract with effective α-glucosidase inhibitory activity. The total content of chlorogenic, caffeic, and pcoumaric acids was the highest in MAB (14.63 ㎎/g ext.). In conclusion, the beneficial activities of the tree sprout extracts with high phenolic acid content were generally high. Our results provide a theoretical basis for the development of health-promoting supplements and functional foods.

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Abstract
Materials and methods
Results and Discussion
Conclusion
References

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