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논문 기본 정보

자료유형
학술저널
저자정보
Seong-Mi So (Jeonju University) Tae-Seok Kang (Jeonju University) Yeong-Hyeon Cho (Jeonju University) Joo-Yeon Kim (Korea Basic Science Institute) Seung-Man Yu (Jeonju University)
저널정보
한국자기학회 Journal of Magnetics Journal of Magnetics Vol.27 No.3
발행연도
2022.9
수록면
315 - 322 (8page)
DOI
10.4283/JMAG.2022.27.3.315

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초록· 키워드

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The aim of this study was to investigate difference in brain metabolites between smokers and non-smokers in the brain insular region related to addiction for men in their twenties. Differences in brain connectivity between the two groups were also determined. A total of 20 males volunteers (10 smokers and 10 nonsmokers) were enrolled for this study. Magnetic resonance spectroscopy (MRS) was performed using a 3.0 Tesla MRI scanner. MRS data of left/right insular brain areas were acquired via point-resolved spectroscopy. A total of 3,096 functional magnetic resonance imaging (fMRI) images were obtained under axial conditions in 2D mode. Non-smokers showed significant differences in glycerophosphorylcholine, total choline, free creatine, and total creatine between left and right insular cortical regions. Differences in concentrations of metabolites in the islet cortex between smokers and non-smokers were higher in the left islet region than in the right insular region of non-smokers. Concentrations of tCr metabolites in the left insular area of non-smokers were higher than those of smokers. In addition, smokers showed higher connectivity in the right gyrus and occipital fusiform regions than non-smokers, whereas non-smokers had stronger connectivity between the left insular cortex area and the frontal role right than smokers. This study is meaningful in that it provides a new strategy using fMRI as well as MRS to identify differences in metabolism between smokers and non-smokers in a specific age group.

목차

1. Introduction
2. Experiment and Method
3. Results
4. Discussions
References

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