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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.3
- 수록면
- 59 - 64 (6page)
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Cudrania tricuspidata Bureau (Moraceae) has been used for physical weakness, impotence and insomnia in traditional Korean medicine. In this study, cudratricusxanthone A and cudraxanthone D were isolated from roots of C. tricuspidata and quantification were achieved by using high performance liquid chromatography (HPLC) method with diode array detector. The isolated compound was identified by NMR analysis and HPLC method was validated by linearity, precision and specificity test. The results showed that calibration curves of two compounds indicated great linearity with a correlation coefficient (R²) of 0.9976 and 0.9995. The limits of detection (LOD) for cudratricusxanthone A and cudraxanthone D were 1.15, 0.11 μg/ml. Intra-day precision of cudratricusxanthone A and cudraxanthone D were 0.32~1.99%, 0.09~3.32% and inter-day precision were 0.59~2.40%, 0.28~1.55% RSD (%) values, respectively. The specificity was confirmed by chromatograph and quantitative contents of cudratricusxanthone A and cudraxanthone D were 0.46±0.02% and 1.53±0.06%. Therefore, this study can be used as a basic research data for the quantitative analysis of derived compounds from roots of C. tricuspidata.
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참고문헌 (21)
참고문헌 신청
Zhen, Y. Y / 1981 / Chinese J. Pharmaceutical Analysis 1:94
Jang, I. M. / 2003 / Treatise on Asian Herbal Medicines / Natural Products Science Seoul National University Press
Cha, J. Y. / 1999 / Antioxidative activities and contents of polyphenolic compound of Cudrania tricuspidata / J Korean Soc Food Nutr 28:1310~1315
Andallu, B. / 2001 / Effect of mulberry (Morus indica L.) therapy on plasma and erythrocyte membrane lipids in patients with type 2diabetes / Clinica Chimica Acta 314:47~53
Yamatake, Y. / 1976 / Pharmacological studies on root bark of mulberry tree (Morus alba L.) / Jpn. J. Pharmacol 26:461~469
Jang, I. M. / 2003 / Treatise on Asian Herbal Medicines / Natural Products Science Seoul National University Press
Cha, J. Y. / 1999 / Antioxidative activities and contents of polyphenolic compound of Cudrania tricuspidata / J Korean Soc Food Nutr 28:1310~1315
Andallu, B. / 2001 / Effect of mulberry (Morus indica L.) therapy on plasma and erythrocyte membrane lipids in patients with type 2diabetes / Clinica Chimica Acta 314:47~53
Yamatake, Y. / 1976 / Pharmacological studies on root bark of mulberry tree (Morus alba L.) / Jpn. J. Pharmacol 26:461~469
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