Objectives: This study explored YouTube"s educational program developed for hypertensive patients in response to the COVID-19 pandemic at a community Hypertension and Diabetes Registration and Education Center and evaluated participant satisfaction. Methods: We conducted content analysis of hypertension-related videos uploaded on the YouTube channel “I Want to Know Blood Vessels!” and descriptive analysis of a cross-sectional study that evaluated the satisfaction of 213 hypertensive patients who watched these videos. Results: From April 2020 to November 2021, the center delivered a total of 25 videos related to hypertension. Most individual educational materials were viewed for seven to nine minutes, whereas the total screening time reached over 3 hours. Readers viewed lifestyle habit videos on exercise (up to 6,530 times) and nutrition (up to 1,400 times) more often than specialized videos on hypertension. Of the participants, 100% were satisfied with non-face-to-face self-management education, whereas 99.5% felt they received help from the contents. Conclusions: The improved accessibility of information and communication through YouTube’s educational strategy can enhance health education and promotion programs, while improving hypertensive patients’ health behavior. However, further research is needed to devise a more appropriate method for developing educational materials based on patient video inquiry patterns and preferences.