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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 14 - 18 (5page)
이용수
이 논문의 연구 히스토리 (5)
2013
The morphological evolution of silicon induced by temperature base on phase field model by multi-physics approach
Linan Zhang
,
Dongchoul Kim
대한기계학회 춘추학술대회
2013.12
학술대회자료
The study of chemotherapeutic drug on cancer cell invasion base on multi-physics and multi-scale model
Linan Zhang
,
Dongchoul Kim
대한기계학회 춘추학술대회
2013.05
학술대회자료
2011
The influence of matrix-degrading enzymes and chemotherapeutic drug on cancer cell invasion and treatment
Linan Zhang
,
Dongchoul Kim
대한기계학회 춘추학술대회
2011.11
학술대회자료
The effect of matrix-degrading enzymes on cancer cell invasion
Linan Zhang
,
Dongchoul Kim
대한기계학회 춘추학술대회
2011.04
학술대회자료
Computational analysis of matrix-degrading enzymes in cancer-cell invasion
Linan Zhang
,
김동철
BioChip Journal
2011.01
학술저널
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초록· 키워드
오류제보하기
Invasion is one of the hallmarks of cancer cells. Cancer cells secrete enzymes and invade the surrounding matrix. In this paper, a new model primary study on the invasive process of cancer cells is presented. Our three-dimensional haptotaxis model consists of a cancer-cell population, matrix-degrading enzymes (MDEs), and the extracellular matrix (ECM), and it describes two procedures for invasion by cancer cells. In the first step, cancer cells secrete MDEs, and in the next step, the secreted MDEs degrade the ECM. The simulation results thoroughly reveal that the degradation of the ECM is an influential process in cancer-cell invasion.
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참고문헌 (28)
참고문헌 신청
Hanahan, D / 2000 / The hallmarks of cancer / Cell 100:57~70
Gerisch, A / 2008 / Mathematical modelling of cancer cell invasion of tissue: Local and non-local models and the effect of adhesion / J. Theor. Biol (250):684~704
Turner, S / 2002 / Intercellular adhesion and cancer invasion: a discrete simulation using the extended Potts model / J. Theor. Biol (216):85~100
DeClerck, Y.A / 2000 / Interactions between tumour cells and stromal cells and proteolytic modification of the extracellular matrix by metalloproteinases in cancer / Eur. J. Cancer (36):1258~1268
Testa, J.E / 1992 / Loss of the metastatic phenotype by a accompanied by increased expression of tissue inhibitor of metalloproteinase-2 / Cancer Res (52):5597~5603
Gerisch, A / 2008 / Mathematical modelling of cancer cell invasion of tissue: Local and non-local models and the effect of adhesion / J. Theor. Biol (250):684~704
Turner, S / 2002 / Intercellular adhesion and cancer invasion: a discrete simulation using the extended Potts model / J. Theor. Biol (216):85~100
DeClerck, Y.A / 2000 / Interactions between tumour cells and stromal cells and proteolytic modification of the extracellular matrix by metalloproteinases in cancer / Eur. J. Cancer (36):1258~1268
Testa, J.E / 1992 / Loss of the metastatic phenotype by a accompanied by increased expression of tissue inhibitor of metalloproteinase-2 / Cancer Res (52):5597~5603
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