Exposure of Infants to Aflatoxin M1 from Mother's Breast Milk in Ilam, Western Iran

Farajollah Maleki; Soghra Abdi; Elaham Davodian; Karimeh Haghani; Salar Bakhtiyari

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자료유형: 학술저널

저자정보: Farajollah Maleki (Ilam University of Medical Sciences) Soghra Abdi (Ilam University of Medical Sciences) Elaham Davodian (Ilam University of Medical Sciences) Karimeh Haghani (Ilam University of Medical Sciences) Salar Bakhtiyari (Ilam University of Medical Sciences)

저널정보: 질병관리본부 Osong Public Health and Research Persptectives Osong Public Health and Research Persptectives Vol.6 No.5

발행연도: 2015.1

수록면: 283 - 287 (5page)

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Objectives: Aflatoxins as a highly toxic group of mycotoxins are present in the environment and foodstuff. These have been reported to cause serious health problems in humans. Since aflatoxin M1 (AFM1) is excreted into breast milk, investigating the exposure of infants to AFM1 is of special concern. Methods: In the present study, breast milk samples were collected from 85 lactating mothers in Ilam province, Iran, and the levels of AFM1 were analyzed using the enzyme-linked immunosorbent assay-based technique. AFM1 was detected in breast milk of all lactating women. The mean contamination level was 5.91 ± 2.031 ng/L, ranging from 2 ng/L to 10 ng/L. Results: Multiple regression analysis indicated no significant associations of consumption of milk and dairy products, meat, fish, legumes, grain products, fruits, and nuts with the concentration of AFM1 in breast milk. Furthermore, no significant association was observed between AFM1 concentration and anthropometric data of infants. Conclusion: In western parts of Iran, lactating mothers and their infants could be at risk of aflatoxin B1 and AFM1 exposure, respectively. Therefore, in Iran, the evaluation of AFM1 in human breast milk as a biomarker for postnatal exposure of infants to this carcinogen requires more attention in different regions and various seasons.

참고문헌 (29)

참고문헌 신청

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