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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소화관운동학회(현 대한소화기능성질환.운동학회) Journal of Neurogastroenterology and Motility (JNM) Journal of Neurogastroenterology and Motility (JNM) Vol.21 No.4
- 발행연도
- 2015.1
- 수록면
- 545 - 551 (7page)
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Background/Aims Patients undergoing cholecystectomy may have small intestinal bacterial overgrowth (SIBO). We investigated the prevalence and characteristics of SIBO in patients with intestinal symptoms following cholecystectomy. Methods Sixty-two patients following cholecystectomy, 145 with functional gastrointestinal diseases (FGIDs), and 30 healthy controls undergoing hydrogen (H2)-methane (CH4) glucose breath test (GBT) were included in the study. Before performing GBT, all patients were interrogated using bowel symptom questionnaire. The positivity to GBT indicating the presence of SIBO, gas types and bowel symptoms were surveyed. Results Post-cholecystectomy patients more often had SIBO as evidenced by a positive (+) GBT than those with FGID and controls (29/62, 46.8% vs 38/145, 26.2% vs 4/30, 13.3%, respectively; P = 0.010). In the gas types, the GBT (H2) + post-cholecystectomy patients was significantly higher than those in FGIDs patients (P = 0.017). Especially, positivity to fasting GBT (H2) among the GBT (H2)+ post-cholecystectomy patients was high, as diagnosed by elevated fasting H2 level. The GBT+ group had higher symptom scores of significance or tendency in abdominal discomfort, bloating, chest discomfort, early satiety, nausea, and tenesmus than those of the GBT negative group. The status of cholecystectomy was the only significant independent factor for predicting SIBO. Conclusions The SIBO with high levels of baseline H2 might be the important etiologic factor of upper GI symptoms for post-cholecystectomy patients.
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참고문헌 (30)
참고문헌 신청
Jaunoo SS / 2010 / Postcholecystectomy syndrome (PCS) / Int J Surg 8:15~17
Mechetina TA / 2011 / Rifaximin application in the overgrowth bacterial syndrome in the small / Eksp Klin Gastroenterol (3):93~100
Bajor A / 2010 / Bile acids: short and long term effects in the intestine / Scand J Gastroenterol 45:645~664
Ghoshal UC / 2014 / Breath tests in the diagnosis of small intestinal bacterial overgrowth in patients with irritable bowel syndrome in comparision with quantitative upper gut as pirate culture / Eur J Gastroenterol Hepatol 26:753~760
Corrazza GR / 1990 / The diagnosis of small bowel bacterial overgrowth. Reliability of jejunal culture and inadequacy of breath hydrogen testing / Gastoenterology 98:302~309
Mechetina TA / 2011 / Rifaximin application in the overgrowth bacterial syndrome in the small / Eksp Klin Gastroenterol (3):93~100
Bajor A / 2010 / Bile acids: short and long term effects in the intestine / Scand J Gastroenterol 45:645~664
Ghoshal UC / 2014 / Breath tests in the diagnosis of small intestinal bacterial overgrowth in patients with irritable bowel syndrome in comparision with quantitative upper gut as pirate culture / Eur J Gastroenterol Hepatol 26:753~760
Corrazza GR / 1990 / The diagnosis of small bowel bacterial overgrowth. Reliability of jejunal culture and inadequacy of breath hydrogen testing / Gastoenterology 98:302~309
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