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Long-Term Results of Catheter-Directed Thrombolysis Combined with Iliac Vein Stenting for Iliofemoral Deep Vein Thrombosis
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논문 기본 정보

Type
Academic journal
Author
박찬 (원광대학교) 소병준 (원광대학교)
Journal
The Korean Society of Vascular Surgery Vascular Specialist International Vascular Specialist International Vol.31 No.2 KCI Accredited Journals
Published
2015.1
Pages
47 - 53 (7page)

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Long-Term Results of Catheter-Directed Thrombolysis Combined with Iliac Vein Stenting for Iliofemoral Deep Vein Thrombosis
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Purpose: We were going to access the effect of catheter-directed thrombolytic therapy (CDT) on post-thrombotic syndrome (PTS) and the long term effects of iliac vein stenting in acute iliofemoral deep vein thrombosis (IFDVT). Materials and Methods: Fifty-six limbs in fifty-one patients (46 unilateral, 5 bilateral) were included from November 2001 through December 2007. Patients were classified based on the method of treatment: with stent implantation (n=37) and without stent implantation (n=19). The Villalta scale was chosen to assess for severity of PTS. The validated outcome measures were compared between the treatment groups. Statistical analysis was estimated according to the Kaplan-Meier test and Pearson chi-square test. Results: Mean age was 57±13 years (range, 27?76 years). Mean follow up duration was 56±12 months (range, 24?144 months). Overall 5-year primary patency rate was 66.1% (77.8% in the stenting group and 42.1% in the non-stenting group) and showed statistically significant difference between the two groups (P=0.02). The recurrence rate of deep vein thrombosis was 10/37 (27.1%) in the stenting group and 11/19 (57.9%) in the non-stenting group, respectively, which showed statistically significant difference between the two groups (P=0.024). Overall incidence of mild PTS was 8/30 (26.7%): 4/13 (30.8%) in the stenting group and 4/17 (23.5%) in the non-stenting group. None of the other factors showed statistically significant difference between the groups. Conclusion: Long term results of CDT in IFDVT were acceptable, and stent implantation to the iliac segment seems to have a good effect on the long term results. Therefore CDT with simultaneous stenting is recommended to improve long term results of IFDVT, if indicated.

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References (27)

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White RH / 2003 / The epidemiology of venous thromboembolism / Circulation 107(23 Suppl 1):I4~I8 google schola Kearon C / 2008 / Antithrombotic therapy for venous thromboembolic disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition) / Chest 133(6 Suppl):454S~545S google schola Ashrani AA / 2009 / Incidence and cost burden of post-thrombotic syndrome / J Thromb Thrombolysis 28:465~476 google schola Kahn SR / 2004 / Relationship between deep venous thrombosis and the postthrombotic syndrome / Arch Intern Med 164:17~26 google schola Prandoni P / 1996 / The long-term clinical course of acute deep venous thrombosis / Ann Intern Med 125:1~7 google schola

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