지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 69 - 74 (6page)
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초록· 키워드
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Backgrounds: House-dust mites are the main cause of allergic rhinitis in Asia, for which immunotherapy (SLIT) is a currently accepted treatment. However, few studies have evaluated the efficiency of SLIT on Asian children with allergic rhinitis for a period longer than one year. The aim of this study was to investigate the efficacy and safety of SLIT for Asian children with allergic rhinitis due to house-dust mites over a 2-year period. Materials and Method: This study included 65 patients who had allergic rhinitis due to Dermatophagoides pteronyssinus and Dermatophagoides farinae. All patients were treated with SLIT (StaloralⓇ). Symptom scores and quality of life were evaluated by using questionnaires over two years. The medication score was assessed monthly by a diary medication card and serologic tests were evaluated before and two years after the start of treatment. Adverse effects and dropout rates were also investigated. Results: All nasal and non-nasal symptoms and quality of life were significantly improved after two years of treatment. Furthermore, the total medication score decreased significantly and the serologic tests showed a significant change two years after the start of SLIT. Although minor adverse effects were reported, no systemic reactions were observed. The dropout rate was 40%. Conclusion: SLIT is an efficient and safe therapeutic tool for a period of two years in Asian children with allergic rhinitis to house-dust mites.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
조양선 / 2010 / Prevalence of Otolaryngologic Diseases in South Korea: Data from the Korea National Health and Nutrition Examination Survey 2008 / Clinical and Experimental Otorhinolaryngology 3(4):183~193
Zhang YM / 2013 / Prevalence and Associated Risk Factors of Allergic Rhinitis in Preschool Children in Beijing / Laryngoscope 123:28~35
Pawankar R / 2008 / Allergic Rhinitis and Its Impact on Asthma in Asia Pacific and the ARIA Update 2008 / The WAO Journal 5(Suppl 3):s212~s217
Kim SY / 2010 / Economic burden of allergic rhinitis in Korea / Am J Rhinol Allergy 24(5):e110~e113
Piconi S / 2010 / Immunological effects of sublingual immunotherapy:clinical efficacy is associated with modulation of programmed cell death ligand 1, IL-10, and IgG4 / J Immunol 185(12):7723~7730
Zhang YM / 2013 / Prevalence and Associated Risk Factors of Allergic Rhinitis in Preschool Children in Beijing / Laryngoscope 123:28~35
Pawankar R / 2008 / Allergic Rhinitis and Its Impact on Asthma in Asia Pacific and the ARIA Update 2008 / The WAO Journal 5(Suppl 3):s212~s217
Kim SY / 2010 / Economic burden of allergic rhinitis in Korea / Am J Rhinol Allergy 24(5):e110~e113
Piconi S / 2010 / Immunological effects of sublingual immunotherapy:clinical efficacy is associated with modulation of programmed cell death ligand 1, IL-10, and IgG4 / J Immunol 185(12):7723~7730
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