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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Purpose: The aim of the study is to evaluate the efficacy of initial red cell distribution width (RDW) levels in the emergency department (ED) in predicting early 28-day mortality and high risk patients for early intervention in patients with upper gastrointestinal hemorrhage (UGIB). Methods: This is a retrospective clinical study including UGIB patients in the ED. All data were collected through electronic medical records. The two major endpoints were early 28-day mortality and high risk patients. We assessed the relationship between initial RDW level and high risk patients and 28-day mortality. Results: A total of 198 patients were analyzed. There were 160 high risk patients (81.8%) and 12 non-survival patients (6.1%). The mean RDW value in high risk patients was higher than in non-risk patients (15.4±2.8 vs. 13.6±1.8%; p<0.0001). Area under curve (AUC) in Receiver-operatory characteristic (ROC) curve for RDW in high risk patients was 0.735 (95% Confidence Interval: 0.649-0.821; p<0.001) with an optimal cutoff value of 13.45% with sensitivity of 69.4% and specificity of 73.7%. The mean value of RDW in non-survivals was higher than in survivals (18.0± 3.3 vs. 14.9±2.6 %; p<0.0001). AUC for RDW in predicting 28-day mortality was 0.793 (95% CI: 0.684-0.902; p<0.001) with an optimal cutoff value of 15.95% with sensitivity of 83.3% and specificity of 71.5%. Conclusion: RDW level in initial state might be helpful in predicting high risk patients for early intervention and 28- day mortality in UGIB in the ED.
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참고문헌 (28)
참고문헌 신청
van Leerdam ME / 2003 / Acute upper GI bleeding : did anything change? Time trend analysis of incidence and outcome of acute upper GI bleeding between 1993/1994 and 2000 / Am J Gastroenterol 98:1494~1499
Laine L / 1994 / Bleeding peptic ulcer / N Engl J Med 331:717~727
Holster IL / 2012 / Management of acute nonvariceal upper gastrointestinal bleeding : current policies and future perspectives / World J Gastroenterol 18:1202~1207
Chiu PW / 2010 / Acute nonvariceal upper gastrointestinal bleeding / Curr Opin Gastroenterol 26:425~428
Henrion J / 2008 / Upper gastrointestinal bleeding: what has changed during the last 20 years? / Gastroenterol Clin Biol 32:839~847
Laine L / 1994 / Bleeding peptic ulcer / N Engl J Med 331:717~727
Holster IL / 2012 / Management of acute nonvariceal upper gastrointestinal bleeding : current policies and future perspectives / World J Gastroenterol 18:1202~1207
Chiu PW / 2010 / Acute nonvariceal upper gastrointestinal bleeding / Curr Opin Gastroenterol 26:425~428
Henrion J / 2008 / Upper gastrointestinal bleeding: what has changed during the last 20 years? / Gastroenterol Clin Biol 32:839~847
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