지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 139 - 143 (5page)
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Purpose: To investigate the clinical significance of gallbladder (GB) wall thickening frequentlyobserved in patients with acute hepatitis A.
Methods: A total of 328 consecutive patients who were diagnosed with acute hepatitis A andunderwent abdominal ultrasonography were enrolled retrospectively. Patients were divided intotwo groups: GB wall thickening (≥3 mm, group A) and no thickening (group B). Group A wassubdivided into two subgroups (GB wall thickening of ≥10 mm, group A-1 and ≥3 mm to <10mm, group A-2). The laboratory results related to liver function, hospitalization duration, andtime to normalization of liver function were compared between the groups.
Results: A total of 230 patients showed GB wall thickening (group A). Besides gamma-glutamyltranspeptidase and alkaline phosphatase, all laboratory results of group A were significantlyhigher than those of group B (P<0.05). Compared with group B, the hospitalization durationand the time to normalization of liver function were significantly longer in group A (P<0.05).
Group A-1 included 146 patients and group A-2 included 84 patients. No significant differencesin laboratory results, hospitalization duration, and time to normalization of liver function werefound between the two subgroups. In the multivariate logistic regression analysis, serum alaninetransaminase, total bilirubin and albumin levels, and hospitalization duration were significantlyassociated with GB wall thickening in patients with hepatitis A.
Conclusion: The presence of GB wall thickening in patients with acute hepatitis A suggests apoorer prognosis irrespective of the degree of GB wall thickening or the degree of liver enzymeelevation.
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참고문헌 (16)
참고문헌 신청
Wasley A / 2006 / Hepatitis A in the era of vaccination / Epidemiol Rev 28:101~111
Kim MY / 2003 / Endoscopic sonographic evaluation of the thickened gallbladder wall in patients with acute hepatitis / J Clin Ultrasound 31:245~249
van Breda Vriesman AC / 2007 / Diffuse gallbladder wall thickening: differential diagnosis / AJR Am J Roentgenol 188:495~501
Maresca G / 1984 / Sonographic patterns of the gallbladder in acute viral hepatitis / J Clin Ultrasound 12:141~146
Juttner HU / 1982 / Thickening of the gallbladder wall in acute hepatitis: ultrasound demonstration / Radiology 142:465~466
Kim MY / 2003 / Endoscopic sonographic evaluation of the thickened gallbladder wall in patients with acute hepatitis / J Clin Ultrasound 31:245~249
van Breda Vriesman AC / 2007 / Diffuse gallbladder wall thickening: differential diagnosis / AJR Am J Roentgenol 188:495~501
Maresca G / 1984 / Sonographic patterns of the gallbladder in acute viral hepatitis / J Clin Ultrasound 12:141~146
Juttner HU / 1982 / Thickening of the gallbladder wall in acute hepatitis: ultrasound demonstration / Radiology 142:465~466
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