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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한마취통증의학회(구 대한마취과학회) Korean Journal of Anesthesiology Korean Journal of Anesthesiology Vol.68 No.4
- 발행연도
- 2015.1
- 수록면
- 379 - 385 (7page)
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초록· 키워드
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Background: Postoperative delirium is a frequent complication in elderly patients undergoing major abdominal surgery and is associated with a poor outcome. We compared postoperative delirium in elderly patients following laparoscopic gastrectomy (LG) versus open gastrectomy (OG). Methods: In total, 130 patients aged ≥ 65 years with gastric cancer undergoing LG and OG were enrolled prospectively. Postoperative delirium and cognitive status were assessed daily using the Confusion Assessment Method (CAM) and Mini-Mental Status Examination (MMSE), respectively, for 3 days postoperatively. For CAM-positive patients, delirium severity was then assessed using the Delirium Index (DI). Results: In total, 123 subjects (LG, n = 60; OG, n = 63) were included in the analysis. In both groups, the overall incidences of postoperative delirium were similar: 31.6% (19/60) in the LG group and 41.2% (26/63) in the OG group. When considering only those with delirium, the severity, expressed as the highest DI score, was similar between the groups. A decline in cognitive function (reduction in MMSE ≥ 2 points from baseline) during 3 days postoperatively was observed in 23 patients in the LG group (38.3%) and 27 patients in the OG group (42.9%) (P = 0.744). In both groups, postoperative cognitive decline was significantly associated with postoperative delirium (P < 0.001). Conclusions: We found that, compared with traditional open gastrectomy, laparoscopic gastrectomy did not reduce either postoperative delirium or cognitive decline in elderly patients with gastric cancer.
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등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
van der Mast RC. / 1999 / Postoperative delirium / Dement Geriatr Cogn Disord 10:401~405
Aizawa K / 2002 / A novel approach to the prevention of postoperative delirium in the elderly after gastrointestinal surgery / Surg Today 32:310~314
Ganai S / 2007 / Adverse outcomes of geriatric patients undergoing abdominal surgery who are at high risk for delirium / Arch Surg 142:1072~1078
Witlox J / 2010 / Delirium in elderly patients and the risk of postdischarge mortality, institutionalization, and dementia : a meat-analysis / JAMA 304:443~451
Murray C / 2012 / Systemic inflammation induces acute working memory deficits in the primed brain : relevance for delirium / Neurobiol Aging 33:603~616
Aizawa K / 2002 / A novel approach to the prevention of postoperative delirium in the elderly after gastrointestinal surgery / Surg Today 32:310~314
Ganai S / 2007 / Adverse outcomes of geriatric patients undergoing abdominal surgery who are at high risk for delirium / Arch Surg 142:1072~1078
Witlox J / 2010 / Delirium in elderly patients and the risk of postdischarge mortality, institutionalization, and dementia : a meat-analysis / JAMA 304:443~451
Murray C / 2012 / Systemic inflammation induces acute working memory deficits in the primed brain : relevance for delirium / Neurobiol Aging 33:603~616
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