지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한마취통증의학회(구 대한마취과학회) Korean Journal of Anesthesiology Korean Journal of Anesthesiology Vol.68 No.3
- 발행연도
- 2015.1
- 수록면
- 267 - 273 (7page)
이용수
초록· 키워드
오류제보하기
Background: The purpose of this study was to evaluate the effect of palonosetron combined with dexamethasone for the prevention of PONV compared to dexamethasone alone in women who received intravenous patient-controlled analgesia (IV-PCA) using fentanyl. Methods: In this randomized, double-blinded, placebo-controlled study, 204 healthy female patients who were scheduled to undergo elective surgery under general anesthesia followed by IV-PCA for postoperative pain control were enrolled. Patients were divided into two groups: the PD group (palonosetron 0.075 mg and dexamethasone 5 mg IV; n = 102) and the D group (dexamethasone 5 mg IV; n = 102). The treatments were given after the induction of anesthesia. The incidence of nausea, vomiting, severity of nausea, and the use of rescue anti-emetics during the first 48 hours after surgery were evaluated. Results: The incidence of PONV was significantly lower in the PD group compared with the D group during the 0–24 hours (43 vs. 59%) and 0–48 hours after surgery (45 vs. 63%) (P < 0.05). The severity of nausea during the 6–24 hours after surgery was significantly less in the PD group compared with the D group (P < 0.05). The incidence of rescue antiemetic used was significantly lower in the PD group than in the D group during the 0–6 hours after surgery (13.1 vs. 24.5%) (P < 0.05). Conclusions: Palonosetron combined with dexamethasone was more effective in preventing PONV compared to dexamethasone alone in women receiving IV-PCA using fentanyl.
목차
등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Gan TJ / 2014 / Consensus guidelines for the management of postoperative nausea and vomiting / Anesth Analg 118:85~113
Rojas C / 2010 / Palonosetron triggers 5-HT(3)receptor internalization and causes prolonged inhibition of receptor function / Eur J Pharmacol 626:193~199
Gralla R / 2003 / Palonosetron improves prevention of chemotherapyinduced nausea and vomiting following moderately emetogenic chemotherapy : results of a double-blind randomized phase III trial comparing single doses of palonosetron with ondansetron / Ann Oncol 14:1570~1577
Moon YE / 2012 / Anti-emetic effect of ondansetron and palonosetron in thyroidectomy: a prospective, randomized, doubleblind study / Br J Anaesth 108:417~422
Tramer MR / 1999 / Efficacy and adverse effects of prophylactic antiemetics during patient-controlled analgesia therapy : a quantitative systematic review / Anesth Analg 88:1354~1361
Rojas C / 2010 / Palonosetron triggers 5-HT(3)receptor internalization and causes prolonged inhibition of receptor function / Eur J Pharmacol 626:193~199
Gralla R / 2003 / Palonosetron improves prevention of chemotherapyinduced nausea and vomiting following moderately emetogenic chemotherapy : results of a double-blind randomized phase III trial comparing single doses of palonosetron with ondansetron / Ann Oncol 14:1570~1577
Moon YE / 2012 / Anti-emetic effect of ondansetron and palonosetron in thyroidectomy: a prospective, randomized, doubleblind study / Br J Anaesth 108:417~422
Tramer MR / 1999 / Efficacy and adverse effects of prophylactic antiemetics during patient-controlled analgesia therapy : a quantitative systematic review / Anesth Analg 88:1354~1361
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
A comparison of palonosetron and dexamethasone for postoperative nausea and vomiting in orthopedic patients receiving patient-controlled epidural analgesia
Korean Journal of Anesthesiology
2017 .01
-
Review of dexamethasone administration for management of complications in postoperative third molar surgery
대한구강악안면외과학회지
2021 .10
-
Dexamethasone alone versus in combination with intra-operative super-hydration for postoperative nausea and vomiting prophylaxis in female patients undergoing laparoscopic cholecystectomy: a randomized clinical trial
Korean Journal of Anesthesiology
2017 .01
-
부인과 복강경 수술에서 고용량 metoclopramide, dexamethasone 병용투여와 haloperidol, midazolam, dexamethasone 병용투여의 수술 후 오심, 구토 예방 효과의 비교
Anesthesia and Pain Medicine
2018 .01
-
소아청소년의 항암화학요법에 의한 오심, 구토 예방에 사용되는 Palonosetron과 Ondansetron의 효과 비교
병원약사회지
2017 .01
-
Efficacy of perineural versus intravenous dexamethasone in prolonging the duration of analgesia when administered with peripheral nerve blocks: a systematic review and meta-analysis
Korean Journal of Anesthesiology
2022 .06
-
A Pilot Study Evaluating Steroid-Induced Diabetes after Antiemetic Dexamethasone Therapy in Chemotherapy-Treated Cancer Patients
Cancer Research and Treatment
2016 .01
-
Efficacy of palonosetron plus dexamethasone in preventing chemotherapy-induced nausea and emesis in patients receiving carboplatin-based chemotherapy for gynecologic cancers: a phase II study by the West Japan Gynecologic Oncology Group (WJGOG 131)
Journal of Gynecologic Oncology
2018 .01
-
A Comparative Randomized Trial on the Optimal Timing of Dexamethasone for Pain Relief after Endoscopic Submucosal Dissection for Early Gastric Neoplasm
Gut and Liver
2016 .01
-
The efficacy of dexamethasone injection on postoperative pain in lower third molar surgery
Journal of dental anesthesia and pain medicine
2016 .01
-
Dexamethasone Inhibits TGF-!1–Induced Cell Migration by Regulating the ERK and AKT Pathways in Human Colon Cancer Cells Via CYR61
Cancer Research and Treatment
2016 .01
-
The effect of using nefopam in fentanyl-based intravenous patient-controlled analgesia on the incidence of postoperative nausea and vomiting in laparoscopic gynecological surgery
Medical Biological Science and Engineering
2021 .01
-
Morphologic changes in the spinal cord following intrathecal palonosetron-HCl injection in rats
Anesthesia and Pain Medicine
2017 .01
-
The effect of combining lidocaine with dexamethasone for attenuating postoperative sore throat, cough, and hoarseness
Anesthesia and Pain Medicine
2016 .01
-
Efficacy of Palonosetron vs. Ramosetron for the Prevention of Postoperative Nausea and Vomiting: A Meta-Analysis of Randomized Controlled Trials
Yonsei Medical Journal
2017 .07
-
Comparison among Three Different Steroid Therapies for Idiopathic Sudden Sensorineural Hearing Loss
대한이비인후-두경부외과학회지
2020 .01
-
Decreased post-operative pain using a sublingual injection of dexamethasone (8 mg) in lower third molar surgery
Journal of dental anesthesia and pain medicine
2017 .01
-
Dexamethasone에 의하여 유발된 근육 위축 생쥐의 비복근 근섬유에서 apoptosis와 염증 반응에 미치는 오미자 추출물의 영향
대한한의학방제학회지
2017 .01
-
Effect of intravenous dexamethasone on the duration of postoperative analgesia for popliteal sciatic nerve block: a randomized, double-blind, placebo-controlled study
Korean Journal of Anesthesiology
2021 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0