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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 1,631 - 1,637 (7page)
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초록· 키워드
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The aim of this study was to investigate a single-institution experience with radical perineal prostatectomy (RPP), radical retropubic prostatectomy (RRP) and minimally invasive radical prostatectomy (MIRP) with respect to onco-surgical outcomes in patients with intermediate-risk (IR; PSA 10-20 ng/mL, biopsy Gleason score bGS 7 or cT2b-2c) and highrisk (HR; PSA >20 ng/mL, bGS ≥8, or ≥cT3) prostate cancer (PCa). We retrospectively reviewed data from 2,581 men who underwent radical prostatectomy for IR and HR PCa (RPP, n = 689; RRP, n = 402; MIRP, n = 1,490 [laparoscopic, n = 206; robot-assisted laparoscopic, n = 1,284]). The proportion of HR PCa was 40.3%, 46.8%, and 49.5% in RPP, RRP, and MIRP (P < 0.001), respectively. The positive surgical margin rate was 23.8%, 26.1%, and 18.7% (P = 0.002) overall, 17.5%, 17.8%, and 8.8% (P < 0.001) for pT2 disease and 41.9%, 44.4%, and 40.0% (P = 0.55) for pT3 disease in men undergoing RPP, RRP, and MIRP, respectively. Biochemical recurrence-free survival rates among RPP, RRP, and MIRP were 73.0%, 70.1%, and 76.8%, respectively, at 5 yr (RPP vs. RPP, P = 0.02; RPP vs. MIRP, P = 0.23). Furthermore, comparable 5-yr metastases-free survival rates were demonstrated for specific surgical approaches (RPP vs. RPP, P = 0.26; RPP vs. MIRP, P = 0.06). RPP achieved acceptable oncological control for IR and HR PCa.
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등록된 정보가 없습니다.
참고문헌 (29)
참고문헌 신청
Rodrigues G / 2012 / Pre-treatment risk stratification of prostate cancer patients : a critical review / Can Urol Assoc J 6:121~127
Cooperberg MR / 2003 / Time trends in clinical risk stratification for prostate cancer: implications for outcomes (data from CaPSURE) / J Urol 170:S21~S25
Ischia J / 2013 / Radical prostatectomy in high-risk prostate cancer / Int J Urol 20:290~300
Eggener SE / 2011 / Predicting 15-year prostate cancer specific mortality after radical prostatectomy / J Urol 185:869~875
Young HH / 1905 / The early diagnosis and radical cure of carcinoma of the prostate : being a study of 40 cases and presentation of a radical operation which was carried out in 4 cases / Bull Johns Hopkins Hosp 16:315~321
Cooperberg MR / 2003 / Time trends in clinical risk stratification for prostate cancer: implications for outcomes (data from CaPSURE) / J Urol 170:S21~S25
Ischia J / 2013 / Radical prostatectomy in high-risk prostate cancer / Int J Urol 20:290~300
Eggener SE / 2011 / Predicting 15-year prostate cancer specific mortality after radical prostatectomy / J Urol 185:869~875
Young HH / 1905 / The early diagnosis and radical cure of carcinoma of the prostate : being a study of 40 cases and presentation of a radical operation which was carried out in 4 cases / Bull Johns Hopkins Hosp 16:315~321
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