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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 932 - 936 (5page)
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초록· 키워드
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The purpose of this study was to determine whether contemporary active surveillance (AS) protocols could sufficiently discriminate significant from indolent tumors in men with lowrisk prostate cancer. We retrospectively analyzed 312 patients with low-risk prostate cancer treated with radical prostatectomy. After exclusion of patients with fewer than 10 cores taken at biopsy and those who received neo-adjuvant treatment, 205 subjects satisfied the final inclusion criteria. Five widely accepted AS protocols were employed in this study. A total of 82.0% of the patients met the inclusion criteria of at least one protocol, and 18% did not meet any criteria of published AS protocols. A significant proportion of patients had non-organ-confined disease (8.6% to 10.6%) or a Gleason score of 7 or greater (18.6% to 23.9%) between the different AS criteria. Among patients who did not meet any AS criteria, 32.4% of patients had a pathologically insignificant cancer. Our results indicated a significant adverse pathology in patients who met the contemporary AS protocols. On the other hand, some patients in whom expectant management would be appropriate did not meet any criteria of published AS protocols. None of the clinical or histological criteria reported to date is able to sufficiently discriminate aggressive tumors from indolent ones.
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등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Bul M / 2012 / Radical prostatectomy for low-risk prostate cancer following initial active surveillance : results from a prospective observational study / Eur Urol 62:195~200
Hayes JH / 2010 / Active surveillance compared with initial treatment for men with low-risk prostate cancer : a decision analysis / JAMA 304:2373~2380
Reese AC / 2013 / Expanded criteria to identify men eligible for active surveillance of low risk prostate cancer at Johns Hopkins : a preliminary analysis / J Urol 190:2033~2038
Cooperberg MR / 2011 / Active surveillance for prostate cancer : progress and promise / J Clin Oncol 29:3669~3676
Tosoian JJ / 2013 / Pathological outcomes in men with low risk and very low risk prostate cancer : implications on the practice of active surveillance / J Urol 190:1218~1222
Hayes JH / 2010 / Active surveillance compared with initial treatment for men with low-risk prostate cancer : a decision analysis / JAMA 304:2373~2380
Reese AC / 2013 / Expanded criteria to identify men eligible for active surveillance of low risk prostate cancer at Johns Hopkins : a preliminary analysis / J Urol 190:2033~2038
Cooperberg MR / 2011 / Active surveillance for prostate cancer : progress and promise / J Clin Oncol 29:3669~3676
Tosoian JJ / 2013 / Pathological outcomes in men with low risk and very low risk prostate cancer : implications on the practice of active surveillance / J Urol 190:1218~1222
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