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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 385 - 389 (5page)
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We evaluated the clinicopathological features and prognosis of 29 cases of prostate ductalcarcinoma was considered to be an aggressive subtype of prostate acinar carcinoma. Weselected 29 cases who were diagnosed prostate ductal carcinoma and had a radicalprostatectomy (RP). The acinar group (n = 116) was selected among 3,980 patients whounderwent a prostatectomy. The acinar group was matched to the ductal group forprostate specific antigen (PSA), clinical stage, Gleason score, and age. The mean (range) ofthe follow-up periods for the ductal and acinar group was 23.8 ± 20.6 and 58 ± 10.5months, respectively. The mean age of the prostate ductal and acinar carcinoma patientswas 67.3 and 67.0 yr and the mean PSA level was 14.7 and 16.2 ng/mL, respectively. Nostatistical differences were evident between groups in terms of the final pathologic stageor positive resection margin rate other than the postoperative Gleason score. A greaterproportion of the ductal group demonstrated a postoperative Gleason score ≥ 8 incomparison with the acinar group (P = 0.024). Additionally, we observed significantprognostic difference in our patient series in biochemical recurrence. The ductal groupshowed a poorer prognosis than the acinar group (P = 0.016). There were no differencessignificantly in terms of final pathology and rate of positive resection margin, but a greaterproportion of the ductal group demonstrated a Gleason score ≥ 8 than the acinar groupafter matching for PSA, Gleason score in biopsy and clinical stage. The ductal group alsoshowed a poorer prognosis.
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참고문헌 (20)
참고문헌 신청
Dube VE / 1973 / Prostatic adenocarcinoma of ductal origin / Cancer 32:402~409
Greene LF / 1979 / Prostatic adenocarcinoma of ductal origin / J Urol 121:303~305
Epstein JI / 1986 / Adenocarcinoma of the prostate with endometrioid features. A light microscopic and immunohistochemical study of ten cases / Cancer 57:111~119
Amin A / 2011 / Pathologic stage of prostatic ductal adenocarcinoma at radical prostatectomy : effect of percentage of the ductal component and associated grade of acinar adenocarcinoma / Am J Surg Pathol 35:615~619
Sanati S / 2009 / Gene expression profiles of ductal versus acinar adenocarcinoma of the prostate / Mod Pathol 22:1273~1279
Greene LF / 1979 / Prostatic adenocarcinoma of ductal origin / J Urol 121:303~305
Epstein JI / 1986 / Adenocarcinoma of the prostate with endometrioid features. A light microscopic and immunohistochemical study of ten cases / Cancer 57:111~119
Amin A / 2011 / Pathologic stage of prostatic ductal adenocarcinoma at radical prostatectomy : effect of percentage of the ductal component and associated grade of acinar adenocarcinoma / Am J Surg Pathol 35:615~619
Sanati S / 2009 / Gene expression profiles of ductal versus acinar adenocarcinoma of the prostate / Mod Pathol 22:1273~1279
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