지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Lapière-type psoriasis (annular pustular psoriasis) is characterized by erythematous, annular form plaques and pustules on a ring-like erythema. A 63-year-old man presented with asymptomatic multiple various sized scaly plaques on whole body. He diagnosed with psoriasis vulgaris 30 years previously and also had diabetes and hypertension. He had intermittent annular erosiove lesions while plaque lesions were repeatedly improved and aggravated. He has been treated with oral cyclosporin, sulfasalazine, antihistamine and topical steroid for 1 year. But there was not significant improvement in skin lesions. So, we decided to treat with ustekinumab monotherapy. However, recurrence of the plaques and annular lesions were still present after the ustekinumab injection six times, so we switched to secukinumab monotherapy. After that, the lesions of plaque type psoriasis were improved, but the annular eruptions still had intermittent recurrence. Biopsy was taken from the lesion and showed hyperkeratosis, subcorneal pustule and spongiform pustule of Kogoj, and perivascular lymphocytic infiltration. Based on clinical and histopathologic features, recurrent Lapière-type psoriasis recalcitrant to biologics was diagnosed.
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