지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아혈액종양학회 Clinical Pediatric Hematology-Oncology Clinical Pediatric Hematology-Oncology Vol.25 No.2
- 발행연도
- 2018.1
- 수록면
- 185 - 190 (6page)
이용수
초록· 키워드
오류제보하기
Unprovoked deep vein thrombosis (DVT) is uncommon in pediatric patients and, among those, combined hereditary thrombophilia is particularly rare. We present a 9-year-old Korean boy who developed lower extremity pain with swelling, and was diagnosed with unprovoked DVT due to hereditary (combined hereditary thrombophilia). Coagulation test revealed antithrombin III and protein S deficiency. The genetic work up confirmed the first case of combined antithrombin III deficiency and protein S deficiency by SERPINC1 heterozygous termination mutation [c.685C＞T (p.Arg229*)] and PROS1 heterozygous missense mutation [c.1597G＞A (p.Val533Met)]. He was treated with continuous heparin and catheter intervention but those were ineffective or transiently effective. His DVT gradually improved only after prolonged anticoagulation.
목차
등록된 정보가 없습니다.
참고문헌 (3)
참고문헌 신청
최형수 / 2016 / Venous thromboembolism in pediatric patients: a single institution experience in Korea / Blood Research 51(3):164~170
Hye Lim Jung / 2016 / Venous thromboembolism in children and adolescents / Blood Research 51(3):149~151
Megan O. Nakashima / 2014 / Hypercoagulable states: an algorithmic approach to laboratory testing and update on monitoring of direct oral anticoagulants / Blood Research 49(2):85~94
Hye Lim Jung / 2016 / Venous thromboembolism in children and adolescents / Blood Research 51(3):149~151
Megan O. Nakashima / 2014 / Hypercoagulable states: an algorithmic approach to laboratory testing and update on monitoring of direct oral anticoagulants / Blood Research 49(2):85~94
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