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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 13 - 24 (12page)
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The aim of this study was to investigate the synergistic effect of cold atmospheric plasma (CAP) treatment and RGD peptide coating for enhancing cellular attachment and proliferation over titanium (Ti) surfaces. The surface structure of CAP-treated and RGD peptide-coated Ti discs were characterized by contact angle goniometer and atomic force microscopy. The effect of such surface modification on human bone marrow derived mesenchymal stem cells (hMSCs) adhesion and proliferation was assessed by cell proliferation and DNA content assays. Besides, hMSCs’ adhesion and morphology on surface modified Ti discs were observed via fluorescent and scanning electron microscopy. RGD peptide coating following CAP treatment significantly enhanced cellular adhesion and proliferation among untreated, CAP-treated and RGD peptide-coated Ti discs. The treatment of Ti surfaces with CAP may contribute to improved RGD peptide coating, which enables increased cellular integrations with the Ti surfaces.
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참고문헌 (71)
참고문헌 신청
Raphel J / 2016 / Engineered protein coatings to improve the osseointegration of dental and orthopaedic implants / Biomaterials 83:269~282
Muhammad Sohail Zafar / 2015 / Oral Tissue Engineering Progress and Challenges / 조직공학과 재생의학 12(6):387~397
Schwartz-Arad D / 2005 / A long-term study of implants supporting overdentures as a model for implant success / J Periodontol 76:1431~1435
Karoussis IK / 2004 / Effect of implant design on survival and success rates of titanium oral implants: a 10-year prospective cohort study of the ITI dental implant system / Clin Oral Implants Res 15:8~17
Geetha M / 2009 / Ti based biomaterials, the ultimate choice for orthopaedic implants-a review / Prog Mater Sci 54:397~425
Muhammad Sohail Zafar / 2015 / Oral Tissue Engineering Progress and Challenges / 조직공학과 재생의학 12(6):387~397
Schwartz-Arad D / 2005 / A long-term study of implants supporting overdentures as a model for implant success / J Periodontol 76:1431~1435
Karoussis IK / 2004 / Effect of implant design on survival and success rates of titanium oral implants: a 10-year prospective cohort study of the ITI dental implant system / Clin Oral Implants Res 15:8~17
Geetha M / 2009 / Ti based biomaterials, the ultimate choice for orthopaedic implants-a review / Prog Mater Sci 54:397~425
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