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자료유형
학술저널
저자정보
황재형 ((학) 가톨릭대학교서울성모병원) In Hye Kim (St. Vincent’s Hospital) Hye Sook Lee (St. Vincent’s Hospital) Dong Sun Park (CEO Hospital) 박찬순 (가톨릭대학교)
저널정보
대한수면학회 sleep medicine research sleep medicine research Vol.9 No.2
발행연도
2018.1
수록면
77 - 82 (6page)

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Background and ObjectiveaaObstructive sleep apnea syndrome (OSAS) is considered to be closely related to systemic in ammation. Resistin levels have been demonstrated to be a measure of systemic in ammation. For children, salivary resistin (SR) sampling is an easy and pain-free meth- od for sample collection and is optimal for multiple sampling. erefore, we aimed to evaluate cor- relations among SR levels, objective polysomnography (PSG) parameters, and subjective sleep symptoms. MethodsaaFi y-six children who attended our clinic over 1 year were enrolled prospectively; these children underwent clinical evaluation, questionnaire studies, and PSG. SR was measured at 2 points: at night before PSG and in the early morning a er PSG. resultsaaThe subjects (n = 56) were divided into the control [n = 23, apnea hypopnea index (AHI) < 1] and OSAS (n = 33, AHI ≥ 1) groups. SR levels after PSG in the OSAS and control groups were similarly higher than that before PSG. ere was no signi cant di erence in SR levels between the two groups and among the control and OSAS subgroups. SR levels in the OSAS sub- groups were not related to AHI, tonsil size, AN (adenoid-nasopharyngeal) ratio, questionnaire re- sults, lowest oxygen saturation, and oxygen desaturation index (ODI). ConclusionsaaSR levels had no signi cant correlation with AHI, scores of the Korean version of modi ed pediatric Epworth Sleepiness Scale, the lowest oxygen saturation, and ODI; SR levels ex- hibited diurnal variations regardless of the presence of OSAS. However, there is no consensus re- garding the relationship between resistin levels and OSAS. Further studies should be pursued in the future.

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