Epidemiology of Oral Lichen Planus in a Cohort of South Indian Population: A Retrospective Study

Soma Susan Varghese; Giju Baby George; Sreenivasan Bargavan Sarojini1; Sankar Vinod; Philips Mathew; Deepu George Mathew; Joseph Sebastian; Arun George

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저자정보: Soma Susan Varghese (Mar Baselios Dental College and Hospital Kothamangalam Ernakulam) Giju Baby George (Mar Baselios Dental College Kothamangalam India) Sreenivasan Bargavan Sarojini1 (Mar Baselios Dental College and Hospital Kothamangalam Ernakulam) Sankar Vinod (Mar Baselios Dental College and Hospital Kothamangalam) Philips Mathew (Department of Oral Medicine and Radiology Government Dental College Kottayam) Deepu George Mathew (Department of Oral Pathology and Microbiology Mar Baselios Dental College Kothamangalam India) Joseph Sebastian (Mar Baselios Dental College and Hospital Kothamangalam Ernakulam) Arun George (Department of Oral and Maxillofacial Surgery Mar Baselios Dental College Kothamangalam India)

저널정보: 대한암예방학회 대한암예방학회지 대한암예방학회지 제21권 제1호

발행연도: 2016.1

수록면: 55 - 59 (5page)

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Background: Oral lichen planus (OLP) is an immune-mediated potentially malignant disorder of the oral cavity. Dysplastic OLP has an altered cytogenic profile and can progress into oral squamous cell carcinoma. The epidemiology of OLP is well-described in several relatively large series from various geographic locations, whereas such series from southern India is rare. The aim of the present study was to determine the epidemiology of OLP in a cohort of South Indian population. Methods: All the case data records of 29,606 patients who visited Mar Baselios Dental College and Hospital, Kerala, India from 2014 to 2015 were retrospectively reviewed. For data review, 122 patients of OLP were selected Estimated were type, number, and location of lesions, clinical manifestation, age of the patient, gender, onset and duration of lesion, stressful life style, habits, skin involvement and associated systemic illness, and presence/absence of dysplasia. Results: When the distribution of OLP among the gender was considered, we found more prevalence in females than males. Fifty-seven percent of patients were associated with stressful lifestyle. Reticular lichen planus was the most common clinical subtype found. Bilateral buccal mucosal was the common site, when the distribution of sites of OLP were compared (P ＜ 0.05). Hypersensitivity reaction was frequently associated with systemic illness with OLP (P ＜ 0.05). Anaplasia was found among 5% of lichen planus lesions. Conclusions: OLP patients had high incidence of hypersensitivity reactions and 5% of OLP lesions showed anaplasia. Long term follow-up is necessary to monitor the recurrence, prognosis, and malignant transformation of OLP.

참고문헌 (18)

참고문헌 신청

Kanemitsu S / 2014 / Oral lichen planus: malignant potential and diagnosis / Oral Sci Int 11:1~7

Murti PR / 1986 / Malignant potential of oral lichen planus: observations in 722patients from India / J Oral Pathol 15:71~77

Mattsson U / 2002 / Oral lichen planus and malignant transformation: is a recall of patients justified? / Crit Rev Oral Biol Med 13:390~396

Sugerman PB / 2002 / Oral lichen planus: causes, diagnosis and management / Aust Dent J 47:290~297

Andreasen JO / 1968 / Oral lichen planus. 1. A clinical evaluation of 115cases / Oral Surg Oral Med Oral Pathol 25:31~42

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