지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 1 - 11 (11page)
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Objective: To test the applicability of the Arbeitsgemeinschaft Gynäkologische Onkologie (AGO) and Memorial Sloan Kettering (MSK) criteria in predicting complete cytoreduction (CC) in patients undergoing secondary cytoreductive surgery (SCS) for recurrent ovarian cancer (ROC). Methods: Data of consecutive patients undergoing SCS were reviewed. The Arbeitsgemeinschaft Gynäkologische Onkologie OVARian cancer study group (AGO-OVAR) and MSK criteria were retrospectively applied. Nomograms, based on AGO criteria, MSK criteria and both AGO and MSK criteria were built in order to assess the probability to achieve CC at SCS. Results: Overall, 194 patients met the inclusion criteria. CC was achieved in 161 (82.9%) patients. According to the AGO-OVAR criteria, we observed that CC was achieved in 87.0% of patients with positive AGO score. However, 45 out of 71 (63.4%) patients who did not fulfilled the AGO score had CC. Similarly, CC was achieved in 87.1%, 61.9% and 66.7% of patients for whom SCS was recommended, had to be considered and was not recommended, respectively. In order to evaluate the predictive value of the AGO-OVAR and MSK criteria we built 2 separate nomograms (c-index: 0.5900 and 0.5989, respectively) to test the probability to achieve CC at SCS. Additionally, we built a nomogram using both the aforementioned criteria (c-index: 0.5857). Conclusion: The AGO and MSK criteria help identifying patients deserving SCS. However, these criteria might be strict, thus prohibiting a beneficial treatment in patients who do not met these criteria. Further studies are needed to clarify factors predicting CC at SCS.
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참고문헌 (22)
참고문헌 신청
Siegel RL / 2017 / Cancer statistics, 2017 / CA Cancer J Clin 67:7~30
Cowan RA / 2017 / A comparative analysis of prediction models for complete gross resection in secondary cytoreductive surgery for ovarian cancer / Gynecol Oncol 145:230~235
van de Laar R / 2015 / External validation of two prediction models of complete secondary cytoreductive surgery in patients with recurrent epithelial ovarian cancer / Gynecol Oncol 137:210~215
Minaguchi T / 2016 / Proposal for selection criteria of secondary cytoreductive surgery in recurrent epithelial ovarian, tubal, and peritoneal cancers / Int J Clin Oncol 21:573~579
Janco JM / 2016 / Performance of AGO score for secondary cytoreduction in a high-volume U.S. center / Gynecol Oncol 141:140~147
Cowan RA / 2017 / A comparative analysis of prediction models for complete gross resection in secondary cytoreductive surgery for ovarian cancer / Gynecol Oncol 145:230~235
van de Laar R / 2015 / External validation of two prediction models of complete secondary cytoreductive surgery in patients with recurrent epithelial ovarian cancer / Gynecol Oncol 137:210~215
Minaguchi T / 2016 / Proposal for selection criteria of secondary cytoreductive surgery in recurrent epithelial ovarian, tubal, and peritoneal cancers / Int J Clin Oncol 21:573~579
Janco JM / 2016 / Performance of AGO score for secondary cytoreduction in a high-volume U.S. center / Gynecol Oncol 141:140~147
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