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논문 기본 정보

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학술저널
저자정보
정기욱 (Department of Gastroenterology University of Ulsan College of Medicine Seoul Korea) Myeognsook Seo (Department of Gastroenterology University of Ulsan College of Medicine Seoul Korea) Young Hwan Cho (Department of Gastroenterology University of Ulsan College of Medicine Seoul Korea) Young-Ok Park (Department of Clinical Nutrition University of Ulsan College of Medicine Seoul Korea) So-Yoon Yoon (Department of Clinical Nutrition University of Ulsan College of Medicine Seoul Korea) JungBok Lee (Department of Clinical Epidemiology and Biostatistics University of Ulsan College of Medicine Seoul) Dong-Hoon Yang (Department of Gastroenterology University of Ulsan College of Medicine Seoul Korea) In Ja Yoon (Department of Gastroenterology University of Ulsan College of Medicine Seoul Korea) So Young Seo (Department of Gastroenterology University of Ulsan College of Medicine Seoul Korea) Hyo Jeong Lee (Department of Gastroenterology University of Ulsan College of Medicine Seoul Korea) Sang Hyoung Park (Department of Gastroenterology University of Ulsan College of Medicine Seoul Korea) Kyung Jo Kim (Department of Gastroenterology University of Ulsan College of Medicine Seoul Korea) Byong Duk Ye (Department of Gastroenterology University of Ulsan College of Medicine Seoul Korea) Jeong-Sik Byeon (Department of Gastroenterology University of Ulsan College of Medicine Seoul Korea) Hwoon-Yong Jung (Department of Gastroenterology University of Ulsan College of Medicine Seoul Korea) Suk-Kyun Yang (Department of Gastroenterology University of Ulsan College of Medicine Seoul Korea) Jin-Ho Kim (Department of Gastroenterology University of Ulsan College of Medicine Seoul Korea) Seung-Jae Myung (Department of Gastroenterology University of Ulsan College of Medicine Seoul Korea)
저널정보
대한소화관운동학회(현 대한소화기능성질환.운동학회) Journal of Neurogastroenterology and Motility (JNM) Journal of Neurogastroenterology and Motility (JNM) Vol.24 No.2
발행연도
2018.1
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307 - 316 (10page)

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Background/Aims Fructose malabsorption (FM) mimics symptoms of irritable bowel syndrome (IBS), and its prevalence has increased. Diagnosing FM in IBS is challenging because of its overlap with small intestinal bacterial overgrowth (SIBO). We assessed the prevalence of FM by comparing patients with IBS with asymptomatic control individuals after excluding SIBO using the glucose hydrogen breath test (HBT). Methods Patients diagnosed with IBS and asymptomatic control individuals were enrolled prospectively. Dietary habits were assessed with the Food Frequency Questionnaire. After excluding SIBO, participants underwent HBTs with both 15 g and 25 g of fructose. Results Thirty-five patients with IBS and 35 age- and sex-matched asymptomatic control individuals were enrolled. The 15-g fructose HBT yielded positive results in 7 of the 35 (20.0%) patients with IBS and in 2 of 35 (5.7%) controls (P = 0.070). The 25-g fructose HBT was positive in 16 of the 35 (45.7%) patients with IBS and in 8 of the 35 (22.9%) controls (P = 0.040). Analysis of the Food Frequency Questionnaire responses showed no significant differences between the 2 groups in dietary intake, although patients with IBS showed a significantly higher mean fiber intake than controls (21.24 ± 11.35 g vs 15.87 ± 7.07 g, respectively, P = 0.040). Conclusions The 25-g fructose HBT identified FM in a significantly higher percentage of SIBO-negative patients with IBS than in asymptomatic control individuals, suggesting that FM may correlate with IBS. Education regarding dietary control of foods containing fructose may be useful for the management of patients with IBS.

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참고문헌 (34)

참고문헌 신청
Gibson PR / 2007 / Review article: fructose malabsorption and the bigger picture / Aliment Pharmacol Ther 25:349~363 google schola Park YK / 1993 / Intakes and food sources of fructose in the United States / Am J Clin Nutr 58(5 suppl):737S~747S Crossref 염혜원 / 2011 / 청소년 대사증후군에서 임상영양치료 / Pediatric Gastroenterology, Hepatology & Nutrition 14(4):350~358 dbpia Densupsoontorn N / 2007 / Fructose malabsorption in Thai adult / Asia Pac J Clin Nutr 16:209~212 google schola Riby JE / 1993 / Fructose absorption / Am J Clin Nutr 58(5 suppl):748S~753S Crossref

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