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학술저널
저자정보
권영근 (고려대학교) 김경진 (고려의대) 노용균 (한림대학교) 박용규 (가톨릭대학교) 박성수 (고려대학교) 조경환 (고려대학교)
저널정보
대한노인병학회 Annals of geriatric medicine and research Annals of geriatric medicine and research Vol.21 No.2
발행연도
2017.1
수록면
70 - 77 (8page)

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Background: The survival benefit of excess body weight is controversial across various subpopulations. We assessed the effect of weight status on all-cause mortality among patients with type 2 diabetes(T2DM) undergoing subtotal gastrectomy for gastric cancer. Methods: Medical charts of 210 patients with T2DM treated at 2 university hospitals were examined retrospectively. All patients had undergone subtotal gastrectomy for cancer between January 1993 and December 2012. Participants were categorized as normal weight(body mass index[BMI], 18.5-24.99kg/m2) or overweight/obese(BMI≥25kg/m2). The association between weight status and all-cause mortality was assessed using weighted Cox proportional hazard regression models and inverse probability weighting. Results: The mortality rate was 25.2% after a median follow-up duration of 6.1 years(in- terquartile range, 3.5-8.3 years; maximum, 14.4 years). The overweight/obese group had a significantly lower risk of all-cause mortality(hazard ratio, 0.51; 95% confidence interval, 0.34-0.77; p=0.001) compared with the normal weight group. Overweight/obesity was associated with reduced all-cause mortality in patients aged <65 years(p=0.01 for interaction). Conclusion: Among T2DM patients who underwent subtotal gastrectomy for cancer, only the subgroup of patients aged <65 years in the overweight/obese group showed reduced all- cause mortality compared with the normal weight group.

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