지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Purpose: This study aimed to examine the prevalence of hyperuricemia in association with relative grip strength and leg strength in Korean Elderly. Methods: We studied cross-sectional analysis with 1,894 rural adults (40−88 years old), who were surveyed for 7 years from 2007 to 2014. Grip strength was measured by using Takei grip strength dynamometer. Leg strength was measured by using Takei leg strength dynamometer. Hyperuricemia was defined by examining serum uric acid concentration (male ≥7 mg/dL, female ≥6 mg/dL). Logistic regression was conducted to evaluate the association of grip strength and leg strength with hyperuricemia (p＜0.05). Results: Subjects who reported high level of relative grip strength had a significantly lower odds ratio (OR) of hyperuricemia than subjects who reported low level of relative grip strength (OR, 0.37; 95% confidence interval [CI], 0.16−0.84). When it comes to sex, subjects both high relative muscle strength are significantly lower multivariate-adjusted OR of hyperuricemia than subjects both low relative muscle strength in male (OR, 0.52; 95% CI, 0.29−0.95) and female (OR, 0.47; 95% CI, 0.26−0.95). Additionally, senior group (age ≥65 years), who have low relative grip strength and high relative leg strength, was only significantly associated with the prevalence of hyperuricemia (OR, 0.43; 95% CI, 0.19−0.98). Conclusion: The relationship between hyperuricemia and relative grip strength may be mediated through decreased estimated glomerular filtration ratio. Therefore, muscle strength is important factor in prevention of renal vascular dysfunction which is a risk factor of hyperuricemia, and resistance exercise is needed to improve muscle strength.
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참고문헌 (24)
참고문헌 신청
Gagliardi AC / 2009 / Uric acid: a marker of increased cardiovascular risk / Atherosclerosis 202:11~17
Trifiro G / 2013 / Epidemiology of gout and hyperuricaemia in Italy during the years 2005-2009: a nationwide population-based study / Ann Rheum Dis 72:694~700
Lim S / 2011 / Increasing prevalence of metabolic syndrome in Korea: the Korean National Health and Nutrition Examination Survey for 1998-2007 / Diabetes Care 34:1323~1328
Zimmet P / 2005 / The metabolic syndrome: a global public health problem and a new definition / J Atheroscler Thromb 12:295~300
Newman AB / 2006 / Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort / J Gerontol A Biol Sci Med Sci 61:72~77
Trifiro G / 2013 / Epidemiology of gout and hyperuricaemia in Italy during the years 2005-2009: a nationwide population-based study / Ann Rheum Dis 72:694~700
Lim S / 2011 / Increasing prevalence of metabolic syndrome in Korea: the Korean National Health and Nutrition Examination Survey for 1998-2007 / Diabetes Care 34:1323~1328
Zimmet P / 2005 / The metabolic syndrome: a global public health problem and a new definition / J Atheroscler Thromb 12:295~300
Newman AB / 2006 / Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort / J Gerontol A Biol Sci Med Sci 61:72~77
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