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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 222 - 231 (10page)
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Background: Despite advances in the treatment of primary cancer, metastatic pathologic fractures still affect the survival of cancer patients. The goals of surgery, such as those with terminal cancer, are to maintain a maximum level of independence and improve the quality of life. A patient may be a poor surgical candidate because of a short life expectancy or illness that is too severe to benefit from surgical fixation. Moreover, this surgery is an operation accompanied with significant morbidity and mortality. This retrospective study investigated the characteristics of these patients and assessed the influence of anesthetic risk factors on the outcome. Methods: The records of 45 patients with pathologic fractures who underwent surgical stabilization for metastatic factors from 1 January 1995 to 31 December 2013 at our hospital were reviewed. Demographic data, various severity scores, anesthetic factors, and survival were reviewed. Results: The most common sites of primary tumors were lung, liver and stomach. The predominant sites of pathologic fractures were the femur (71.1%); six lesions were in the humerus and four in the spine. Univariate and multivariate analyses identified several prognostic factors with a significantly worse influence on survival, including lung tumor and Acute Physiology and Chronic Health Evaluation (APACHE) II score. Conclusions: Although the number of patients was too small to result in a satisfactory appraisal, the most important step is to select candidates to gain the benefits of palliative surgery. We suggest the possibility of APACHE II scoring and the recognition of lung cancer in making the clinical decision of performing the palliative osteosyntheses for patients with pathologic fractures.
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참고문헌 (30)
참고문헌 신청
Snyder BD / 2009 / Noninvasive prediction of fracture risk in patients with metastatic cancer to the spine / Clin Cancer Res 15:7676~7683
Sarahrudi K / 2009 / Surgical treatment of metastatic fractures of the femur: a retrospective analysis of 142 patients / J Trauma 66:1158~1163
Saad F / 2007 / Pathologic fractures correlate with reduced survival in patients with malignant bone disease / Cancer 110:1860~1867
Hirsh V / 2009 / Skeletal disease contributes substantially to morbidity and mortality in patients with lung cancer / Clin Lung Cancer 10:223~229
Reich CD / 2003 / Advances in the treatment of bone metastases / Clin J Oncol Nurs 7:641~646
Sarahrudi K / 2009 / Surgical treatment of metastatic fractures of the femur: a retrospective analysis of 142 patients / J Trauma 66:1158~1163
Saad F / 2007 / Pathologic fractures correlate with reduced survival in patients with malignant bone disease / Cancer 110:1860~1867
Hirsh V / 2009 / Skeletal disease contributes substantially to morbidity and mortality in patients with lung cancer / Clin Lung Cancer 10:223~229
Reich CD / 2003 / Advances in the treatment of bone metastases / Clin J Oncol Nurs 7:641~646
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