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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 1 - 8 (8page)
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Background: Limb salvage surgery with vascular reconstruction is currently considered as the standard treatment for extremity soft tissue sarcoma (STS), showing equivalent oncologic outcome compared with amputation. In this retrospective study, the surgical and functional outcomes after arterial or venous reconstruction in limb salvage surgery for STS were analyzed. Methods: Consecutive patients who underwent vascular resection and reconstruction as part of limb salvage surgery for extremity STS from July 2009 to June 2015 were included in this study. Incidence of surgical complication, graft patency, and patients' functional outcome were reviewed. Results: During the study period, 14 arteries and 13 veins were reconstructed in 17 patients (artery only in 4, vein only in 3, artery and vein in 10). Autologous great saphenous vein (GSV) was the most commonly used vascular conduit in both arterial and venous reconstruction (78.6% and 77.0%). The patency of synthetic graft was significantly lower than that of the autologous vein conduit (log rank test, P = 0.001). Among 15 patients with tumors in lower extremity, 13 were ambulatory after limb salvage surgery. During median follow up of 23.3 months (interquartile range 39.9 months), 2 patients (11.7%) needed amputation of the initially salvaged limb due to local recurrence. Conclusion: Limb salvage surgery of soft tissue tumor combined with vascular reconstruction showed favorable functional outcome with good local control. Autologous vein conduit is preferred over synthetic graft both in arterial and venous reconstruction.
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참고문헌 (14)
참고문헌 신청
Lawrence W Jr / 1988 / Concepts in limb-sparing treatment of adult soft tissue sarcomas / Semin Surg Oncol 4(1):73~77
Schwarzbach MH / 2005 / Results of limb-sparing surgery with vascular replacement for soft tissue sarcoma in the lower extremity / J Vasc Surg 42(1):88~97
Nagarajan R / 2002 / Limb salvage and amputation in survivors of pediatric lower-extremity bone tumors: what are the long-term implications? / J Clin Oncol 20(22):4493~4501
Williard WC / 1992 / Comparison of amputation with limb-sparing operations for adult soft tissue sarcoma of the extremity / Ann Surg 215(3):269~275
Karakousis CP / 1995 / Primary soft tissue sarcoma of the extremities in adults / Br J Surg 82(9):1208~1212
Schwarzbach MH / 2005 / Results of limb-sparing surgery with vascular replacement for soft tissue sarcoma in the lower extremity / J Vasc Surg 42(1):88~97
Nagarajan R / 2002 / Limb salvage and amputation in survivors of pediatric lower-extremity bone tumors: what are the long-term implications? / J Clin Oncol 20(22):4493~4501
Williard WC / 1992 / Comparison of amputation with limb-sparing operations for adult soft tissue sarcoma of the extremity / Ann Surg 215(3):269~275
Karakousis CP / 1995 / Primary soft tissue sarcoma of the extremities in adults / Br J Surg 82(9):1208~1212
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